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This paper introduces a deep neural network based method, i.e., DeepOrganNet, to generate and visualize fully high-fidelity 3D / 4D organ geometric models from single-view medical images with complicated background in real time. Traditional 3D / 4D medical image reconstruction requires near hundreds of projections, which cost insufferable computational time and deliver undesirable high imaging / radiation dose to human subjects. Moreover, it always needs further notorious processes to segment or extract the accurate 3D organ models subsequently. The computational time and imaging dose can be reduced by decreasing the number of projections, but the reconstructed image quality is degraded accordingly. To our knowledge, there is no method directly and explicitly reconstructing multiple 3D organ meshes from a single 2D medical grayscale image on the fly. Given single-view 2D medical images, e.g., 3D / 4D-CT projections or X-ray images, our end-to-end DeepOrganNet framework can efficiently and effectively reconstruct 3D / 4D lung models with a variety of geometric shapes by learning the smooth deformation fields from multiple templates based on a trivariate tensor-product deformation technique, leveraging an informative latent descriptor extracted from input 2D images. The proposed method can guarantee to generate high-quality and high-fidelity manifold meshes for 3D / 4D lung models; while, all current deep learning based approaches on the shape reconstruction from a single image cannot. The major contributions of this work are to accurately reconstruct the 3D organ shapes from 2D single-view projection, significantly improve the procedure time to allow on-the-fly visualization, and dramatically reduce the imaging dose for human subjects. Experimental results are evaluated and compared with the traditional reconstruction method and the state-of-the-art in deep learning, by using extensive 3D and 4D examples, including both synthetic phantom and real patient datasets. The efficiency of the proposed method shows that it only needs several milliseconds to generate organ meshes with 10K vertices, which has great potential to be used in real-time image guided radiation therapy (IGRT). 

This paper introduces a new unified particle-based formulation for resamplings with specific patterns from original point clouds. Given the input point clouds, the proposed Lp-Gaussian kernel function is defined to simulate the inter-particle energy and force to form the isotropic/adaptive/anisotropic hexagonal and quadrilateral sampling patterns. Then, the particle-based optimization can be easily formulated and computed in parallel scheme with the high-efficiency and the fast convergence, without any control of particle population. Finally, based on the optimized particle distribution, the high-quality surface meshes are reconstructed by computing the restricted Voronoi diagram and its dual mesh with the parallel implementation. The experimental results are demonstrated by using extensive examples and evaluation criteria as well as compared with the state-of-the-art in the point cloud resampling and reconstruction. 

Analyzing the geometric and semantic properties of 3D point clouds through the deep networks is still challenging due to the irregularity and sparsity of samplings of their geometric structures. This paper presents a new method to define and compute convolution directly on 3D point clouds by the proposed annular convolution. This new convolution operator can better capture the local neighborhood geometry of each point by specifying the (regular and dilated) ring-shaped structures and directions in the computation. It can adapt to the geometric variability and scalability at the signal processing level. We apply it to the developed hierarchical neural networks for object classification, part segmentation, and semantic segmentation in large-scale scenes. The extensive experiments and comparisons demonstrate that our approach outperforms the state-of-the-art methods on a variety of standard benchmark datasets (e.g., ModelNet10, ModelNet40, ShapeNetpart, S3DIS, and ScanNet).