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Introductory biochemistry courses are often challenging for students because they require the integration of chemistry, biology, physics, math, and physiology knowledge and frameworks to understand and apply a large body of knowledge. This can be complicated by students' persistent misconceptions of fundamental concepts and lack of fluency with the extensive visual and symbolic literacy used in biochemistry. Card sorting tasks and game‐based activities have been used to reveal insights into how students are assimilating, organizing, and structuring disciplinary knowledge, and how they are progressing along a continuum from disciplinary novice to expert. In this study, game‐based activities and card sorting tasks were used to promote and evaluate students' understanding of fundamental structure–function relationships in biochemistry. Our results suggest that while many markers of expertise increased for both the control and intervention groups over the course of the semester, students involved in the intervention activities tended to move further towards expert‐like sorting. This indicates that intentional visual literacy game‐based activities have the ability to build underdeveloped skills in undergraduate students.

 

While molecular visualization has been recognized as a threshold concept in biology education, the explicit assessment of students' visual literacy skills is rare. To facilitate the evaluation of this fundamental ability, a series of NSF‐IUSE‐sponsored workshops brought together a community of faculty engaged in creating instruments to assess students' biomolecular visualization skills. These efforts expanded our earlier work in which we created a rubric describing overarching themes, learning goals, and learning objectives that address student progress toward biomolecular visual literacy. Here, the BioMolViz Steering Committee (BioMolViz.org) documents the results of those workshops and uses social network analysis to examine the growth of a community of practice. We also share many of the lessons we learned as our workshops evolved, as they may be instructive to other members of the scientific community as they organize workshops of their own.

 

From the perspective of a novice student, the molecular biosciences are inherently invisible. A challenge facing bioscience educators is to help students create detailed mental models of the biomolecules that make up a living cell and how they all work together to support life. With the advancement of rapid-prototyping, also known as 3D (three dimensional)-printing, physical models of biomolecules are entering undergraduate classrooms as tools to aid in constructing mental models of biological phenomena at the molecular-level.This relatively new pedagogical tool requires evidence-based practices for optimal use in aiding student conceptual and visual development.This chapter presents current evidence for the use of physical models as learning tools, while also introducing case studies on how physical models of biomolecules are designed and assessed in undergraduate molecular bioscience settings.