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  1. Abstract Poisson’s equation is the canonical elliptic partial differential equation. While there exist fast Poisson solvers for finite difference (FD) and finite element methods, fast Poisson solvers for spectral methods have remained elusive. Here we derive spectral methods for solving Poisson’s equation on a square, cylinder, solid sphere and cube that have optimal complexity (up to polylogarithmic terms) in terms of the degrees of freedom used to represent the solution. Whereas FFT-based fast Poisson solvers exploit structured eigenvectors of FD matrices, our solver exploits a separated spectra property that holds for our carefully designed spectral discretizations. Without parallelization we can solve Poisson’s equation on a square with 100 million degrees of freedom in under 2 min on a standard laptop. 
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  3. We review recent advances in algorithms for quadrature, transforms, differential equations and singular integral equations using orthogonal polynomials. Quadrature based on asymptotics has facilitated optimal complexity quadrature rules, allowing for efficient computation of quadrature rules with millions of nodes. Transforms based on rank structures in change-of-basis operators allow for quasi-optimal complexity, including in multivariate settings such as on triangles and for spherical harmonics. Ordinary and partial differential equations can be solved via sparse linear algebra when set up using orthogonal polynomials as a basis, provided that care is taken with the weights of orthogonality. A similar idea, together with low-rank approximation, gives an efficient method for solving singular integral equations. These techniques can be combined to produce high-performance codes for a wide range of problems that appear in applications. 
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