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  1. Free, publicly-accessible full text available November 1, 2025
  2. Free, publicly-accessible full text available November 1, 2025
  3. Accurate medical imaging segmentation is critical for precise and effective medi- cal interventions. However, despite the success of convolutional neural networks (CNNs) in medical image segmentation, they still face challenges in handling fine-scale features and variations in image scales. These challenges are particularly evident in complex and challenging segmentation tasks, such as the BraTS multi- label brain tumor segmentation challenge. In this task, accurately segmenting the various tumor sub-components, which vary significantly in size and shape, remains a significant challenge, with even state-of-the-art methods producing substantial errors. Therefore, we propose two architectures, FMG-Net and W-Net, that incor- porate the principles of geometric multigrid methods for solving linear systems of equations into CNNs to address these challenges. Our experiments on the BraTS 2020 dataset demonstrate that both FMG-Net and W-Net outperform the widely used U-Net architecture regarding tumor subcomponent segmentation accuracy and training efficiency. These findings highlight the potential of incorporating the principles of multigrid methods into CNNs to improve the accuracy and efficiency of medical imaging segmentation. 
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  4. Medical imaging deep learning models are often large and complex, requiring specialized hardware to train and evaluate these models. To address such issues, we propose the PocketNet paradigm to reduce the size of deep learning models by throttling the growth of the number of channels in convolutional neural networks. We demonstrate that, for a range of segmentation and classification tasks, PocketNet architectures produce results comparable to that of conventional neural networks while reducing the number of parameters by multiple orders of magnitude, using up to 90% less GPU memory, and speeding up training times by up to 40%, thereby allowing such models to be trained and deployed in resource-constrained settings. 
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  5. The analyses of interior penalty discontinuous Galerkin methods of any order k for solving elliptic and parabolic problems with Dirac line sources are presented. For the steady state case, we prove convergence of the method by deriving a priori error estimates in the L 2 norm and in weighted energy norms. In addition, we prove almost optimal local error estimates in the energy norm for any approximation order. Further, almost optimal local error estimates in the L 2 norm are obtained for the case of piecewise linear approximations whereas suboptimal error bounds in the L 2 norm are shown for any polynomial degree. For the time-dependent case, convergence of semi-discrete and of backward Euler fully discrete scheme is established by proving error estimates in L 2 in time and in space. Numerical results for the elliptic problem are added to support the theoretical results. 
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