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Award ID contains: 2151966

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  1. (, University of Houston)
    The diaphragm is a crucial muscle in respiration, creating the pressure gradients necessary for inhalation. This thesis focuses on a computational methodology to reconstruct the diaphragm’s geometry using CT imaging and simulate its biomechanical behavior under physiological loading via Finite Element Analysis (FEA). ITK-SNAP was used for medical image segmentation, CATIA V5 for 3D reconstruction, and ANSYS for simulation under various pressure scenarios. The reconstructed diaphragm model was validated against anatomical landmarks and literature-based deformation ranges, showing good agreement. The proposed workflow provides a robust approach for modeling soft tissue biomechanics. 
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    Free, publicly-accessible full text available July 22, 2026
  2. ; (, SSRN Elsevier http://dx.doi.org/10.2139/ssrn.4860096)
    A comprehensive constitutive theory is developed for the diaphragm. The theory can describe the mechanical properties of the diaphragm muscle in its passive and active states in a unified manner. It also describes the mechanical properties of the diaphragm under mechanical loads in arbitrary directions. The theoretical model involves seven material constants that represent the nonlinear elastic moduli and activation strains of the diaphragm muscle. The values of these material constants are determined by using in vitro experimental data, including that from shear loading experiments which are documented in this work for the first time. 
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    Free, publicly-accessible full text available June 11, 2026
  3. ; (, Journal of Biomechanics)
    Full Text Available