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6-Carboxycellulose Acetate Butyrate: Effectiveness as an Amorphous Solid Dispersion Polymer

https://doi.org/10.1021/acs.molpharmaceut.4c00493

Marks, Joyann A; Nichols, Brittany_L B; Mosquera-Giraldo, Laura I; T_Yazdi, Sara; Taylor, Lynne S; Edgar, Kevin J (September 2024, Molecular Pharmaceutics)

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Selective cross-metathesis of cellobiose derivatives with amido-functionalized olefinic structures: A model study for synthesis of cellulosic diblock copolymers

https://doi.org/10.1016/j.carbpol.2024.122274

Sato, Yuuki; Sugimura, Kazuki; Edgar, Kevin J; Kamitakahara, Hiroshi (September 2024, Carbohydrate Polymers)

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Reductive amination of oxidized hydroxypropyl cellulose with ω-aminoalkanoic acids as an efficient route to zwitterionic derivatives

https://doi.org/10.1016/j.carbpol.2023.121699

Zhou, Yang; Yao, Yimin; Zhai, Zhenghao; Mohamed, Mennatallah A.; Mazzini, Fiorella; Qi, Qingqing; Bortner, Michael J.; Taylor, Lynne S.; Edgar, Kevin J. (March 2024, Carbohydrate Polymers)

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Smart fluorescent polysaccharides: Recent developments and applications

https://doi.org/10.1016/j.carbpol.2023.121471

Novo, Diana C.; Edgar, Kevin J. (January 2024, Carbohydrate Polymers)

Polysaccharides are ubiquitous, generally benign in nature, and compatible with many tissues in biomedical situations, making them appealing candidates or new materials such as therapeutic agents and sensors. Fluorescent labeling can create the ability to sensitively monitor distribution and transport o polysaccharide-based materials, which can or example urther illuminate drug-delivery mechanisms and thereore improve design o delivery systems. Herein, we review uorophore selection and ways o appending polysaccharides, utility o the product uorescent polysaccharides as new smart materials, and their stimulus-responsive nature, with ocus on their biomedical applications as environment-sensitive biosensors, imaging, and as molecular rulers. Further, we discuss the advantages and disadvantages o these methods, and uture prospects or creation and use o these sel-reporting materials.
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