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The combination of protein and polysaccharides with magnetic materials has been implemented in biomedical applications for decades. Proteins such as silk, collagen, and elastin and polysaccharides such as chitosan, cellulose, and alginate have been heavily used in composite biomaterials. The wide diversity in the structure of the materials including their primary monomer/amino acid sequences allow for tunable properties. Various types of these composites are highly regarded due to their biocompatible, thermal, and mechanical properties while retaining their biological characteristics. This review provides information on protein and polysaccharide materials combined with magnetic elements in the biomedical space showcasing the materials used, fabrication methods, and their subsequent applications in biomedical research.
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Smart fluorescent polysaccharides: Recent developments and applications
Polysaccharides are ubiquitous, generally benign in nature, and compatible with many tissues in biomedical situations, making them appealing candidates or new materials such as therapeutic agents and sensors. Fluorescent labeling can create the ability to sensitively monitor distribution and transport o polysaccharide-based materials, which can or example urther illuminate drug-delivery mechanisms and thereore improve design o delivery systems. Herein, we review uorophore selection and ways o appending polysaccharides, utility o the product uorescent polysaccharides as new smart materials, and their stimulus-responsive nature, with ocus on their biomedical applications as environment-sensitive biosensors, imaging, and as molecular rulers. Further, we discuss the advantages and disadvantages o these methods, and uture prospects or creation and use o these sel-reporting materials.
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- Award ID(s):
- 2204996
- PAR ID:
- 10493741
- Publisher / Repository:
- Elsevier
- Date Published:
- Journal Name:
- Carbohydrate Polymers
- Volume:
- 324
- Issue:
- C
- ISSN:
- 0144-8617
- Page Range / eLocation ID:
- 121471
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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- Free Publicly Accessible Full Text
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Accepted Manuscript1.0
- Journal Article:
- https://doi.org/10.1016/j.carbpol.2023.121471
