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1. Catalytic, Enantioselective syn- Diamination of Alkenes

   https://doi.org/10.1021/jacs.9b11261  

   Tao, Zhonglin; Gilbert, Bradley B.; Denmark, Scott E. (December 2019, Journal of the American Chemical Society)
2. Catalytic, Enantioselective Syn -Oxyamination of Alkenes

   https://doi.org/10.1021/jacs.1c06750  

   Mumford, Emily M.; Hemric, Brett N.; Denmark, Scott E. (August 2021, Journal of the American Chemical Society)
3. Synthesis of N -tosylaziridines from substituted alkenes via zirconooxaziridine catalysis

   https://doi.org/10.1039/D2CC00686C  

   Pinarci, Ali A.; Daniecki, Noah; TenHoeve, Tyler M.; Dellosso, Brandon; Madiu, Rufai; Mejia, Liliana; Bektas, Seda E.; Moura-Letts, Gustavo (April 2022, Chemical Communications)

   Herein we report the zirconooxaziridine promoted aziridination of alkenes using chloramine T as the quantitative source of N. The reaction works with high yields, diastereoselectivities and stereospecificity for a wide variety of substituted alkenes. A potential mechanism involving the formation of a zirconooxaziridine complex as the active catalyst has been proposed and initial mechanistic data would indicate that a highly associative mechanism is the predominant pathway for this transformation. 

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4. Synthesis of aminoalcohols from substituted alkenes via tungstenooxaziridine catalysis

   https://doi.org/10.1039/d4ob00022f  

   Madiu, Rufai; Dellosso, Brandon; Doran, Erin L.; Doran, Jenna M.; Pinarci, Ali A.; TenHoeve, Tyler M.; Howard, Amari M.; Stroud, James L.; Rivera, Dominic A.; Moskovitz, Dylan A.; et al (March 2024, Organic & Biomolecular Chemistry)

   Novel tungstenooxaziridine complex promotes the oxyamination of substituted alkenes with high stereoselectivity and stereospecificity. Mechanistic studies provide evidence for a highly selectivesyn-difunctionalization pathway. 

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5. Electrocatalytic redox neutral [3 + 2] annulation of N -cyclopropylanilines and alkenes

   https://doi.org/10.1039/d0sc05665k  

   Wang, Qi; Wang, Qile; Zhang, Yuexiang; Mohamed, Yasmine M.; Pacheco, Carlos; Zheng, Nan; Zare, Richard N.; Chen, Hao (January 2021, Chemical Science)

   null (Ed.)

   Although synthetic organic electrochemistry (EC) has advanced significantly, net redox neutral electrosynthesis is quite rare. Two approaches have been employed to achieve this type of electrosynthesis. One relies on turnover of the product by the reactant in a chain mechanism. The other involves both oxidation on the anode and reduction on the cathode in which the radical cation or the radical anion of the product has to migrate between two electrodes. Herein, a home-built electrochemistry/mass spectrometry (EC/MS) platform was used to generate an N -cyclopropylaniline radical cation electrochemically and to monitor its reactivity toward alkenes by mass spectrometry (MS), which led to the discovery of a new redox neutral reaction of intermolecular [3 + 2] annulation of N -cyclopropylanilines and alkenes to provide an aniline-substituted 5-membered carbocycle via direct electrolysis (yield up to 81%). A chain mechanism, involving the regeneration of the substrate radical cation and the formation of the neutral product, is shown to be responsible for promoting such a redox neutral annulation reaction, as supported by experimental evidence of EC/MS. 

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