Abstract Phylodynamics is an area of population genetics that uses genetic sequence data to estimate past population dynamics. Modern state‐of‐the‐art Bayesian nonparametric methods for recovering population size trajectories of unknown form use either change‐point models or Gaussian process priors. Change‐point models suffer from computational issues when the number of change‐points is unknown and needs to be estimated. Gaussian process‐based methods lack local adaptivity and cannot accurately recover trajectories that exhibit features such as abrupt changes in trend or varying levels of smoothness. We propose a novel, locally adaptive approach to Bayesian nonparametric phylodynamic inference that has the flexibility to accommodate a large class of functional behaviors. Local adaptivity results from modeling the log‐transformed effective population size a priori as a horseshoe Markov random field, a recently proposed statistical model that blends together the best properties of the change‐point and Gaussian process modeling paradigms. We use simulated data to assess model performance, and find that our proposed method results in reduced bias and increased precision when compared to contemporary methods. We also use our models to reconstruct past changes in genetic diversity of human hepatitis C virus in Egypt and to estimate population size changes of ancient and modern steppe bison. These analyses show that our new method captures features of the population size trajectories that were missed by the state‐of‐the‐art methods.
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Culture Process and the Interpretation of Radiocarbon Data
Abstract Over the last decade, archaeologists have turned to large radiocarbon ( 14 C) data sets to infer prehistoric population size and change. An outstanding question concerns just how direct of an estimate 14 C dates are for human populations. In this paper we propose that 14 C dates are a better estimate of energy consumption, rather than an unmediated, proportional estimate of population size. We use a parametric model to describe the relationship between population size, economic complexity and energy consumption in human societies, and then parametrize the model using data from modern contexts. Our results suggest that energy consumption scales sub-linearly with population size, which means that the analysis of a large 14 C time-series has the potential to misestimate rates of population change and absolute population size. Energy consumption is also an exponential function of economic complexity. Thus, the 14 C record could change semi-independent of population as complexity grows or declines. Scaling models are an important tool for stimulating future research to tease apart the different effects of population and social complexity on energy consumption, and explain variation in the forms of 14 C date time-series in different regions.
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- Award ID(s):
- 1520308
- PAR ID:
- 10101488
- Date Published:
- Journal Name:
- Radiocarbon
- Volume:
- 60
- Issue:
- 2
- ISSN:
- 0033-8222
- Page Range / eLocation ID:
- 453 to 467
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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