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   https://doi.org/10.1021/acs.chemrev.2c00344  

   Li, Qingsi; Wen, Chiyu; Yang, Jing; Zhou, Xianchi; Zhu, Yingnan; Zheng, Jie; Cheng, Gang; Bai, Jie; Xu, Tong; Ji, Jian; et al (December 2022, Chemical Reviews)
2. Zwitterionic Biomaterials

   Q. Li, C. Wen (January 2022, Chemical reviews)

   The term “zwitterionic polymers” refers to polymers that bear a pair of oppositely charged groups in their repeating units. When these oppositely charged groups are equally distributed at the molecular level, the molecules exhibit an overall neutral charge with a strong hydration effect via ionic solvation. The strong hydration effect constitutes the foundation of a series of exceptional properties of zwitterionic materials, including resistance to protein adsorption, lubrication at interfaces, promotion of protein stabilities, antifreezing in solutions, etc. As a result, zwitterionic materials have drawn great attention in biomedical and engineering applications in recent years. In this review, we give a comprehensive and panoramic overview of zwitterionic materials, covering the fundamentals of hydration and nonfouling behaviors, different types of zwitterionic surfaces and polymers, and their biomedical applications. 

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3. Biomaterials for Hemostasis

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   Simpson, Aryssa; Shukla, Anita; Brown, Ashley C. (June 2022, Annual Review of Biomedical Engineering)

   Uncontrolled bleeding is a major problem in trauma and emergency medicine. While materials for trauma applications would certainly find utility in traditional surgical settings, the unique environment of emergency medicine introduces additional design considerations, including the need for materials that are easily deployed in austere environments. Ideally, these materials would be available off the shelf, could be easily transported, and would be able to be stored at room temperature for some amount of time. Both natural and synthetic materials have been explored for the development of hemostatic materials. This review article provides an overview of classes of materials used for topical hemostats and newer developments in the area of injectable hemostats for use in emergency medicine. Expected final online publication date for the Annual Review of Biomedical Engineering, Volume 24 is June 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates. 

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4. Fluorinated peptide biomaterials

   https://doi.org/10.1002/pep2.24184  

   Sloand, Janna N.; Miller, Michael A.; Medina, Scott H. (July 2020, Peptide Science)

   Abstract Fluorinated compounds, while rarely used by nature, are emerging as fundamental ingredients in biomedical research, with applications in drug discovery, metabolomics, biospectroscopy, and, as the focus of this review, peptide/protein engineering. Leveraging the fluorous effect to direct peptide assembly has evolved an entirely new class of organofluorine building blocks from which unique and bioactive materials can be constructed. Here, we discuss three distinct peptide fluorination strategies used to design and induce peptide assembly into nano‐, micro‐, and macro‐supramolecular states that potentiate high‐ordered organization into material scaffolds. These fluorine‐tailored peptide assemblies employ the unique fluorous environment to boost biofunctionality for a broad range of applications, from drug delivery to antibacterial coatings. This review provides foundational tactics for peptide fluorination and discusses the utility of these fluorous‐directed hierarchical structures as material platforms in diverse biomedical applications. 

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5. Designer biomaterials for mechanobiology

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   Li, Linqing; Eyckmans, Jeroen; Chen, Christopher S. (November 2017, Nature Materials)