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1. Age-related similarities and differences in cognitive and neural processing revealed by task-related microstate analysis

   https://doi.org/10.1016/j.neurobiolaging.2024.01.007  

   Denaro, Chandlyr M.; Reed, Catherine L.; Joshi, Jasmin; Petropoulos, Astrid; Thapar, Anjali; Hartley, Alan A. (April 2024, Neurobiology of Aging)

   We explored neural processing differences associated with aging across four cognitive functions. In addition to ERP analysis, we included task-related microstate analyses, which identified stable states of neural activity across the scalp over time, to explore whole-head neural activation differences. Younger and older adults (YA, OA) completed face perception (N170), word-pair judgment (N400), visual oddball (P3), and flanker (ERN) tasks. Age-related effects differed across tasks. Despite age-related delayed latencies, N170 ERP and microstate analyses indicated no age-related differences in amplitudes or microstates. However, age-related condition differences were found for P3 and N00 amplitudes and scalp topographies: smaller condition differences were found for in OAs as well as broader centroparietal scalp distributions. Age group comparisons for the ERN revealed similar focal frontocentral activation loci, but differential activation patterns. Our findings of differential age effects across tasks are most consistent with the STAC-r framework which proposes that age-related effects differ depending on the resources available and the kinds of processing and cognitive load required of various tasks. 

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2. Greater sleep variance related to decrements in memory performance and event-specific neural similarity: a racially/ethnically diverse lifespan sample

   Hokett, E; Mirjalili, S; Duarte, A (October 2022, Neurobiology of aging)

   Successful memory performance depends on overlap between neural representations at encoding and retrieval. With older age, neural similarity, memory performance, and sleep quality decline. Regardless of age, racial/ethnic minorities tend to experience poor sleep, which may contribute to poor memory. Previous studies have not investigated memory performance, neural similarity, sleep quality, and age in diverse participants. Here, we recruited racially/ethnically diverse adults across the lifespan and examined night-to-night sleep quality in relation to memory performance and encoding-retrieval similarity. We employed item-specific, representational similarity analysis (not confounded by effort, word perception, or differences in electroencephalography signal amplitude) to assess neural similarity for intact and recombined paired associates. Greater sleep variance and poorer memory performance were more strongly associated with older age. Interestingly, sleep variance was positively associated with neural similarity for intact pairs. This relationship was stronger with younger age and for racial/ethnic minorities. For recombined pairs, greater sleep variance was associated with reduced neural similarity. Thus, varied sleep may induce greater reliance on familiarity, while consistent sleep may support recollection. 

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3. Advancing with age: Older adults excel in comprehension of novel metaphors.

   https://doi.org/10.1037/pag0000836  

   Ichien, Nicholas; Stamenković, Dušan; Whatley, Mary C; Castel, Alan D; Holyoak, Keith J (June 2024, Psychology and Aging)

   Older adults may experience certain forms of cognitive decline, but some forms of semantic memory remain intact in older age. To address how metaphor comprehension changes with age and whether metaphor comprehension relies more heavily on analogical reasoning (supported by fluid intelligence) or on conceptual combination (supported by crystalized intelligence), we compared performance of younger and older adults. In two experiments, healthy older adults (54–88 years) scored lower on a measure of fluid intelligence (Ravens Progressive Matrices) but higher on a measure of crystalized intelligence (Mill Hill Vocabulary Test) relative to younger adults (18–34 years). Groups were equally successful in comprehending relatively easy metaphors (Study 1), but older adults showed a striking advantage over younger adults for novel literary metaphors (Study 2). Mixed-effects modeling showed that measures of fluid and crystalized intelligence each made separable contributions to metaphor comprehension for both groups, but older adults relied more on crystalized intelligence than did younger adults. These age-related dissociations clarify cognitive effects of aging and highlight the importance of crystalized intelligence for metaphor comprehension in both younger and older adults. 

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4. Age-related variability in network engagement during music listening

   https://doi.org/10.1162/netn_a_00333  

   Faber, Sarah E. M.; Belden, Alexander G.; Loui, Psyche; McIntosh, Randy (December 2023, Network Neuroscience)

   Abstract Listening to music is an enjoyable behaviour that engages multiple networks of brain regions. As such, the act of music listening may offer a way to interrogate network activity, and to examine the reconfigurations of brain networks that have been observed in healthy aging. The present study is an exploratory examination of brain network dynamics during music listening in healthy older and younger adults. Network measures were extracted and analyzed together with behavioural data using a combination of hidden Markov modelling and partial least squares. We found age- and preference-related differences in fMRI data collected during music listening in healthy younger and older adults. Both age groups showed higher occupancy (the proportion of time a network was active) in a temporal-mesolimbic network while listening to self-selected music. Activity in this network was strongly positively correlated with liking and familiarity ratings in younger adults, but less so in older adults. Additionally, older adults showed a higher degree of correlation between liking and familiarity ratings consistent with past behavioural work on age-related dedifferentiation. We conclude that, while older adults do show network and behaviour patterns consistent with dedifferentiation, activity in the temporal-mesolimbic network is relatively robust to dedifferentiation. These findings may help explain how music listening remains meaningful and rewarding in old age. 

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5. Reactive, Agentic, Apathetic, or Challenged? Aging, Emotion, and Coping During the COVID-19 Pandemic

   https://doi.org/10.1093/geront/gnaa196  

   Young, Nathaniel A; Waugh, Christian E; Minton, Alyssa R; Charles, Susan T; Haase, Claudia M; Mikels, Joseph A (December 2020, The Gerontologist)

   Meeks, Suzanne (Ed.)

   Abstract Background and Objectives Advanced age is generally associated with improved emotional well-being, but the coronavirus 2019 pandemic unleashed a global stressor that gravely threatened the physical well-being and ostensibly challenged the emotional well-being of older adults disproportionately. The current study investigated differences in emotional experiences and coping strategies between younger and older adults during the pandemic, and whether these differences were accounted for by age differences in appraisal of the pandemic. Research Design and Methods We asked younger (n = 181) and older (n = 176) adult participants to report their stress, appraisals of the pandemic, emotions, and the ways in which they were coping with the pandemic. Results Results indicated that older adults experienced less stress and less negative affect and used greater problem-focused coping and less avoidant coping in response to the pandemic than younger adults. Furthermore, age differences in affect and coping were partially accounted for by age differences in appraisals of the pandemic. Discussion and Implications Despite their objectively higher risk of illness and death due to the pandemic, older adults experienced less negative affect and used more agentic coping strategies than younger adults. 

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