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Abstract As scientists, we are at least as excited about the open questions—the things we do not know—as the discoveries. Here, we asked 15 experts to describe the most compelling open questions in plant cell biology. These are their questions: How are organelle identity, domains, and boundaries maintained under the continuous flux of vesicle trafficking and membrane remodeling? Is the plant cortical microtubule cytoskeleton a mechanosensory apparatus? How are the cellular pathways of cell wall synthesis, assembly, modification, and integrity sensing linked in plants? Why do plasmodesmata open and close? Is there retrograde signaling from vacuoles to the nucleus? How do root cells accommodate fungal endosymbionts? What is the role of cell edges in plant morphogenesis? How is the cell division site determined? What are the emergent effects of polyploidy on the biology of the cell, and how are any such “rules” conditioned by cell type? Can mechanical forces trigger new cell fates in plants? How does a single differentiated somatic cell reprogram and gain pluripotency? How does polarity develop de-novo in isolated plant cells? What is the spectrum of cellular functions for membraneless organelles and intrinsically disordered proteins? How do plants deal with internal noise? How does order emerge in cells and propagate to organs and organisms from complex dynamical processes? We hope you find the discussions of these questions thought provoking and inspiring.
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Designing Domain Specific Computing Systems
Domain specific computing is an idea that has been pro-posed as a path forward given the slowing of Moore’s Law and the breakdown of Dennard scaling. Two fundamental questions include: (1) how does one define a domain; and (2) how does one go about architecting hardware that performs well for that domain? We present our preliminary work towards answering these questions.
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- Award ID(s):
- 1763503
- PAR ID:
- 10183996
- Date Published:
- Journal Name:
- IEEE 28th Annual International Symposium on Field-Programmable Custom Computing Machines (FCCM)
- Page Range / eLocation ID:
- 221 to 221
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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- Free Publicly Accessible Full Text
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Accepted Manuscript1.0
- Conference Paper:
- https://doi.org/10.1109/FCCM48280.2020.00052
