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Title: Variation of In Vivo Anisotropic MRE Metrics in Corpus Callosum: Effect of Aging
Healthy aging involves local variations in viscoelastic shear properties of the brain. We employ high-resolution, multi-excitation MRE and a novel anisotropic inversion scheme (iTI) to extract local shear anisotropic moduli in vivo. The ratio of transverse to axial moduli, a new MRE metric, remains greater than 1 along the splenium, body and genu regions of the corpus callosum for both young and old subjects. This metric peaks in the body region and decreases with age throughout the corpus callosum.  more » « less
Award ID(s):
1762774
NSF-PAR ID:
10208447
Author(s) / Creator(s):
Date Published:
Journal Name:
Proceedings of the International Society for Magnetic Resonance in Medicine Scientific Meeting and Exhibition
ISSN:
1524-6965
Page Range / eLocation ID:
0164
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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