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Title: Striosomes Mediate Value-Based Learning Vulnerable in Age and a Huntington's Disease Model.
In Brief: Friedman et al. find that specializedregions of the striatum, a key part of thebrain’s movement and motivation controlsystem, are essential for learning aboutthe values of good and bad outcomes ofdecisions. The learning signals instriosomes scale according to subjectivevalue and are vulnerable to decline withaging and in neurodegenerativedisorders.  more » « less
Award ID(s):
1810758
PAR ID:
10228855
Author(s) / Creator(s):
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Date Published:
Journal Name:
Cell
ISSN:
1097-4172
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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