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Title: Catalyst carbonylation: a hidden, but essential, step in reaction initiation
The proliferation of increasingly useful reactions for hydrogen transfer in organic synthesis has included the introduction of many new homogeneous catalysts into the organic synthesis lexicon. Unlike the proliferation of palladium-based cross-coupling reactions in which the mechanism is generally conserved, we are learning that these emerging hydrogen transfer catalysts have a rich diversity of mechanisms for catalyst activation, speciation, C–H bond cleavage and formation, and ultimately deactivation. We find that an underappreciated commonality in the catalytic activation for some of these systems is the generation of a (carbonyl)metal group, which dominates the downstream speciation of the catalyst system. In this mini-review we highlight a few well-documented cases of this phenomenon as food for thought for those who are designing new catalytic systems to introduce into this dynamic and impactful area.  more » « less
Award ID(s):
1856395
PAR ID:
10229630
Author(s) / Creator(s):
; ; ; ;
Date Published:
Journal Name:
Catalysis Science & Technology
Volume:
11
Issue:
7
ISSN:
2044-4753
Page Range / eLocation ID:
2361 to 2368
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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