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Title: Background-free dual-mode optical and 13 C magnetic resonance imaging in diamond particles
Multimodal imaging—the ability to acquire images of an object through more than one imaging mode simultaneously—has opened additional perspectives in areas ranging from astronomy to medicine. In this paper, we report progress toward combining optical and magnetic resonance (MR) imaging in such a “dual” imaging mode. They are attractive in combination because they offer complementary advantages of resolution and speed, especially in the context of imaging in scattering environments. Our approach relies on a specific material platform, microdiamond particles hosting nitrogen vacancy (NV) defect centers that fluoresce brightly under optical excitation and simultaneously “hyperpolarize” lattice C 13 nuclei, making them bright under MR imaging. We highlight advantages of dual-mode optical and MR imaging in allowing background-free particle imaging and describe regimes in which either mode can enhance the other. Leveraging the fact that the two imaging modes proceed in Fourier-reciprocal domains (real and k-space), we propose a sampling protocol that accelerates image reconstruction in sparse-imaging scenarios. Our work suggests interesting possibilities for the simultaneous optical and low-field MR imaging of targeted diamond nanoparticles.
Authors:
; ; ; ; ; ; ; ; ; ; ; ; ; ;
Award ID(s):
1903839 1903803
Publication Date:
NSF-PAR ID:
10230757
Journal Name:
Proceedings of the National Academy of Sciences
Volume:
118
Issue:
21
Page Range or eLocation-ID:
e2023579118
ISSN:
0027-8424
Sponsoring Org:
National Science Foundation
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