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Title: Laser spectroscopic technique for direct identification of a single virus I: FASTER CARS
From the famous 1918 H1N1 influenza to the present COVID-19 pandemic, the need for improved viral detection techniques is all too apparent. The aim of the present paper is to show that identification of individual virus particles in clinical sample materials quickly and reliably is near at hand. First of all, our team has developed techniques for identification of virions based on a modular atomic force microscopy (AFM). Furthermore, femtosecond adaptive spectroscopic techniques with enhanced resolution via coherent anti-Stokes Raman scattering (FASTER CARS) using tip-enhanced techniques markedly improves the sensitivity [M. O. Scully, et al ., Proc. Natl. Acad. Sci. U.S.A. 99, 10994–11001 (2002)].  more » « less
Award ID(s):
2013771
PAR ID:
10284753
Author(s) / Creator(s):
; ; ; ; ; ; ; ;
Date Published:
Journal Name:
Proceedings of the National Academy of Sciences
Volume:
117
Issue:
45
ISSN:
0027-8424
Page Range / eLocation ID:
27820 to 27824
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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