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Title: Hydroxyl radical is a significant player in oxidative DNA damage in vivo
Recent publications have suggested that oxidative DNA damage mediated by hydroxyl radical (˙OH) is unimportant in vivo , and that carbonate anion radical (CO 3 ˙ − ) plays the key role. We examine these claims and summarize the evidence that ˙OH does play a key role as an important member of the reactive oxygen species (ROS) in vivo .  more » « less
Award ID(s):
1920110
NSF-PAR ID:
10286750
Author(s) / Creator(s):
; ; ;
Date Published:
Journal Name:
Chemical Society Reviews
Volume:
50
Issue:
15
ISSN:
0306-0012
Page Range / eLocation ID:
8355 to 8360
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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