Similarity of the non-amyloid-β component and C-terminal tail of monomeric and tetrameric alpha-synuclein with 14-3-3 sigma
                        
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            null (Ed.)The tensor rank and border rank of the $$3 \times 3$$ determinant tensor are known to be $$5$$ if the characteristic is not two. In characteristic two, the existing proofs of both the upper and lower bounds fail. In this paper, we show that the tensor rank remains $$5$$ for fields of characteristic two as well.more » « less
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            Abstract Fluorinated oxindoles are frequently used building blocks in asymmetric synthesis and represent an important scaffold found in a variety of biologically relevant compounds. While it is understood that incorporation of fluorine atoms into organic molecules can improve their pharmacological properties, the impact on the configurational stability of chiral organofluorines is still underexplored. In this study, semipreparative HPLC enantioseparations of five oxindoles were carried out, and the resulting enantiomerically enriched solutions were used to investigate base promoted racemization kinetics at room temperature. It was found that incorporation of fluorine at the chiral center increases the configurational stability, while substitutions on the aromatic ring and at the lactam moiety also have significant effects on the rate of racemization, which generally follows reversible first‐order reaction kinetics.more » « less
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