An official website of the United States government
Deformable microchannels emulate a key characteristic of soft biological systems and flexible engineering devices: the flow-induced deformation of the conduit due to slow viscous flow within. Elucidating the two-way coupling between oscillatory flow and deformation of a three-dimensional (3-D) rectangular channel is crucial for designing lab-on-a-chip and organ-on-a-chip microsystems and eventually understanding flow–structure instabilities that can enhance mixing and transport. To this end, we determine the axial variations of the primary flow, pressure and deformation for Newtonian fluids in the canonical geometry of a slender (long) and shallow (wide) 3-D rectangular channel with a deformable top wall under the assumption of weak compliance and without restriction on the oscillation frequency (i.e. on the Womersley number). Unlike rigid conduits, the pressure distribution is not linear with the axial coordinate. To validate this prediction, we design a polydimethylsiloxane-based experimental platform with a speaker-based flow-generation apparatus and a pressure acquisition system with multiple ports along the axial length of the channel. The experimental measurements show good agreement with the predicted pressure profiles across a wide range of the key dimensionless quantities: the Womersley number, the compliance number and the elastoviscous number. Finally, we explore how the nonlinear flow–deformation coupling leads to self-induced streaming (rectification of the oscillatory flow). Following Zhang and Rallabandi (J. Fluid Mech., vol. 996, 2024, p. A16), we develop a theory for the cycle-averaged pressure based on the primary problem’s solution, and we validate the predictions for the axial distribution of the streaming pressure against the experimental measurements.
more »
« less
Soft hydraulics: from Newtonian to complex fluid flows through compliant conduits
Abstract Microfluidic devices manufactured from soft polymeric materials have emerged as a paradigm for cheap, disposable and easy-to-prototype fluidic platforms for integrating chemical and biological assays and analyses. The interplay between the flow forces and the inherently compliant conduits of such microfluidic devices requires careful consideration. While mechanical compliance was initially a side-effect of the manufacturing process and materials used, compliance has now become a paradigm, enabling new approaches to microrheological measurements, new modalities of micromixing, and improved sieving of micro- and nano-particles, to name a few applications. This topical review provides an introduction to the physics of these systems. Specifically, the goal of this review is to summarize the recent progress towards a mechanistic understanding of the interaction between non-Newtonian (complex) fluid flows and their deformable confining boundaries. In this context, key experimental results and relevant applications are also explored, hand-in-hand with the fundamental principles for their physics-based modeling. The key topics covered include shear-dependent viscosity of non-Newtonian fluids, hydrodynamic pressure gradients during flow, the elastic response (deformation and bulging) of soft conduits due to flow within, the effect of cross-sectional conduit geometry on the resulting fluid–structure interaction, and key dimensionless groups describing the coupled physics. Open problems and future directions in this nascent field of soft hydraulics, at the intersection of non-Newtonian fluid mechanics, soft matter physics, and microfluidics, are noted.
more »
« less
- Award ID(s):
- 1705637
- PAR ID:
- 10303122
- Date Published:
- Journal Name:
- Journal of Physics: Condensed Matter
- Volume:
- 34
- Issue:
- 6
- ISSN:
- 0953-8984
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
More Like this
-
-
Surfactants are often added to particle suspensions in the flow of Newtonian or non-Newtonian fluids for the purpose of reducing particle-particle aggregation and particle-wall adhesion. However, the impact on the flow behavior of such surfactant additions is often overlooked. We experimentally investigate the effect of the addition of a frequently used neutral surfactant, Tween 20, at the concentration pertaining to microfluidic applications on the entry flow of water and three common polymer solutions through a planar cavity microchannel. We find that the addition of Tween 20 has no significant influence on the shear viscosity or extensional flow of Newtonian water and Boger polyethylene oxide solution. However, such a surfactant addition reduces both the shear viscosity and shear-thinning behavior of xanthan gum and polyacrylamide solutions that each exhibit a strong shear-thinning effect. It also stabilizes the cavity flow and delays the onset of flow instability in both cases. The findings of this work can directly benefit microfluidic applications of particle and cell manipulation in Newtonian and non-Newtonian fluids.more » « less
-
Interactions between fluid flow and elastic structures are important in many naturally occurring and engineered systems. This review collects and organizes recent theoretical and experimental developments in understanding fluid-structure interactions at low Reynolds numbers. Particular attention is given to the motion of objects moving in close proximity to deformable soft materials and the ensuing interplay between fluid flow and elastic deformation. We discuss how this interplay can be understood in terms of forces and torques, and harnessed in applications such as microrheometry, tribology, and soft robotics. We then discuss the interaction of soft and wet objects close to contact, where intermolecular forces and surface roughness effects become important and are sources of complexity and opportunity.more » « less
-
Summary In this paper, a three‐dimensional numerical solver is developed for suspensions of rigid and soft particles and droplets in viscoelastic and elastoviscoplastic (EVP) fluids. The presented algorithm is designed to allow for the first time three‐dimensional simulations of inertial and turbulent EVP fluids with a large number particles and droplets. This is achieved by combining fast and highly scalable methods such as an FFT‐based pressure solver, with the evolution equation for non‐Newtonian (including EVP) stresses. In this flexible computational framework, the fluid can be modeled by either Oldroyd‐B, neo‐Hookean, FENE‐P, or Saramito EVP models, and the additional equations for the non‐Newtonian stresses are fully coupled with the flow. The rigid particles are discretized on a moving Lagrangian grid, whereas the flow equations are solved on a fixed Eulerian grid. The solid particles are represented by an immersed boundary method with a computationally efficient direct forcing method, allowing simulations of a large numbers of particles. The immersed boundary force is computed at the particle surface and then included in the momentum equations as a body force. The droplets and soft particles on the other hand are simulated in a fully Eulerian framework, the former with a level‐set method to capture the moving interface and the latter with an indicator function. The solver is first validated for various benchmark single‐phase and two‐phase EVP flow problems through comparison with data from the literature. Finally, we present new results on the dynamics of a buoyancy‐driven drop in an EVP fluid.more » « less
-
Three-dimensional (3D) printing has emerged as a transformative technology for fabricating complex microfluidic devices, enabling features that were previously unattainable with traditional layer-by-layer soft lithography. One key challenge in advancing 3D-printed microfluidics is the integration of functional microvalves across multiple spatial orientations. This study explores the design, simulation, and experimental realization of novel microvalve configurations to overcome the limitations of conventional, single-plane valves. We hypothesize that non-traditional valve orientations, such as those with vertically printed membranes or perpendicular control channels, present unique fabrication and operational challenges, including membrane delamination and stress-induced failure. To address these issues, we developed optimized geometries and fabrication techniques, supported by computational fluid dynamics (CFD) simulations to predict and mitigate stress concentrations. Our results demonstrate successful implementation of previously unreported valve configurations, validated through pressure testing and flow control experiments. These advancements expand the versatility of 3D-printed microfluidic systems, paving the way for more robust and adaptable devices in biomedical, chemical, and environmental applications.more » « less
- Free Publicly Accessible Full Text
-
Accepted Manuscript1.0
- Journal Article:
- https://doi.org/10.1088/1361-648X/ac327d
