skip to main content
US FlagAn official website of the United States government
dot gov icon
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
https lock icon
Secure .gov websites use HTTPS
A lock ( lock ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.


Title: A Conformational Study of the 10-23 DNAzyme via Programmed DNA Self-Assembly
This communication measures the inter-helical angle of the 10-23 DNAzyme-substrate complex by atomic force microscopy (AFM). specificity. Herein, we have devised a strategy to assemble the DNAzyme-substrate complex into a periodic DNA 2D array, which allows reliable study of the conformation of the 10-23 DNAzyme by AFM imaging and fast Fourier transform (FFT). Specifically, the angle between the two flanking helical domains of the catalytic core has been determined via the repeating distance of 2D array. We expect that the same strategy can generally be applicable for studying other nucleic acid structures.  more » « less
Award ID(s):
2107393 2106790 2107267 2025187
PAR ID:
10323885
Author(s) / Creator(s):
; ; ; ;
Date Published:
Journal Name:
Chemical Communications
ISSN:
1359-7345
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
More Like this
  1. Abstract 2D photonic crystal (PhC) lasing from an InP nanowire array still attached to the InP substrate is demonstrated for the first time. The undoped wurtzite InP nanowire array is grown by selective area epitaxy and coated with a 10 nm thick Al2O3film to suppress atmospheric oxidation and band‐bending effects. The PhC array displays optically pumped lasing at room temperature at a pulsed threshold fluence of 14 µJ cm−2. At liquid nitrogen temperature, the array shows lasing under continuous wave excitation at a threshold intensity of 500 W cm−2. The output power of the single mode laser line reaches values of 470 µW. Rate equation calculations indicate a quality factor ofQ ≈ 1000. Investigations near threshold reveal that lasing starts from isolated islands within the pumped region before coherently merging into a single homogeneous area with increasing excitation power. This field emits a lasing mode with an average off‐normal angle of ≈6°. Single mode lasing with the nanoarray still attached to the InP substrate opens new design opportunities for electrically pumped PhC laser light sources. 
    more » « less
  2. Abstract Recent progress in stretchable forms of inorganic electronic systems has established a route to new classes of devices, with particularly unique capabilities in functional biointerfaces, because of their mechanical and geometrical compatibility with human tissues and organs. A reliable approach to physically and chemically protect the electronic components and interconnects is indispensable for practical applications. Although recent reports describe various options in soft, solid encapsulation, the development of approaches that do not significantly reduce the stretchability remains an area of continued focus. Herein, a generic, soft encapsulation strategy is reported, which is applicable to a wide range of stretchable interconnect designs, including those based on two‐dimensional (2D) serpentine configurations, 2D fractal‐inspired patterns, and 3D helical configurations. This strategy forms the encapsulation while the system is in a prestrained state, in contrast to the traditional approach that involves the strain‐free configuration. A systematic comparison reveals that substantial enhancements (e.g., ≈6.0 times for 2D serpentine, ≈4.0 times for 2D fractal, and ≈2.6 times for 3D helical) in the stretchability can be achieved through use of the proposed strategy. Demonstrated applications in highly stretchable light‐emitting diodes systems that can be mounted onto complex curvilinear surfaces illustrate the general capabilities in functional device systems. 
    more » « less
  3. Abstract Two‐dimensional (2D) antiferromagnetic (AFM) semiconductors are promising components of opto‐spintronic devices due to terahertz operation frequencies and minimal interactions with stray fields. However, the lack of net magnetization significantly limits the number of experimental techniques available to study the relationship between magnetic order and semiconducting properties. Here, they demonstrate conditions under which photocurrent spectroscopy can be employed to study many‐body magnetic excitons in the 2D AFM semiconductor NiI2. The use of photocurrent spectroscopy enables the detection of optically dark magnetic excitons down to bilayer thickness, revealing a high degree of linear polarization that is coupled to the underlying helical AFM order of NiI2. In addition to probing the coupling between magnetic order and dark excitons, this work provides strong evidence for the multiferroicity of NiI2down to bilayer thickness, thus demonstrating the utility of photocurrent spectroscopy for revealing subtle opto‐spintronic phenomena in the atomically thin limit. 
    more » « less
  4. null (Ed.)
    Key properties of two-dimensional (2D) layered materials are highly strain tunable, arising from bond modulation and associated reconfiguration of the energy bands around the Fermi level. Approaches to locally controlling and patterning strain have included both active and passive elastic deformation via sustained loading and templating with nanostructures. Here, by float-capturing ultrathin flakes of single-crystal 2H-MoS2 on amorphous holey silicon nitride substrates, we find that highly symmetric, high-fidelity strain patterns are formed. The hexagonally arranged holes and surface topography combine to generate highly conformal flake-substrate coverage creating patterns that match optimal centroidal Voronoi tessellation in 2D Euclidean space. Using TEM imaging and diffraction, as well as AFM topographic mapping, we determine that the substrate-driven 3D geometry of the flakes over the holes consists of symmetric, out-of-plane bowl-like deformation of up to 35 nm, with in-plane, isotropic tensile strains of up to 1.8% (measured with both selected-area diffraction and AFM). Atomistic and image simulations accurately predict spontaneous formation of the strain patterns, with van der Waals forces and substrate topography as the input parameters. These results show that predictable patterns and 3D topography can be spontaneously induced in 2D materials captured on bare, holey substrates. The method also enables electron scattering studies of precisely aligned, substrate-free strained regions in transmission mode. 
    more » « less
  5. Effects of helical-shaped blades on the flow characteristics and power production of finite-length wind farms composed of vertical-axis wind turbines (VAWTs) are studied numerically using large-eddy simulation (LES). Two helical-bladed VAWTs (with opposite blade twist angles) are studied against one straight-bladed VAWT in different array configurations with coarse, intermediate, and tight spacings. Statistical analysis of the LES data shows that the helical-bladed VAWTs can improve the mean power production in the fully developed region of the array by about 4.94%–7.33% compared with the corresponding straight-bladed VAWT cases. The helical-bladed VAWTs also cover the azimuth angle more smoothly during the rotation, resulting in about 47.6%–60.1% reduction in the temporal fluctuation of the VAWT power output. Using the helical-bladed VAWTs also reduces the fatigue load on the structure by significantly reducing the spanwise bending moment (relative to the bottom base), which may improve the longevity of the VAWT system to reduce the long-term maintenance cost. 
    more » « less