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Title: X-ray photoemission studies of the interaction of metals and metal ions with DNA
Abstract X-ray Photoelectron Spectroscopy (XPS) has been used to study the interactions of heavy metal ions with DNA with some success. Surface sensitivity and selectivity of XPS are advantageous for identifying and characterizing the chemical and elemental structure of the DNA to metal interaction. This review summarizes the status of what amounts to a large part of the photoemission investigations of biomolecule interactions with metals and offers insight into the mechanism for heavy metal-bio interface interactions. Specifically, it is seen that metal interaction with DNA results in conformational changes in the DNA structure.  more » « less
Award ID(s):
2003057 1827690
PAR ID:
10328047
Author(s) / Creator(s):
; ; ;
Date Published:
Journal Name:
Zeitschrift für Physikalische Chemie
Volume:
236
Issue:
4
ISSN:
0942-9352
Page Range / eLocation ID:
439 to 480
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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