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The past decade has brought many innovations in optical design for 3D super-resolution imaging of point-like emitters, but these methods often focus on single-emitter localization precision as a performance metric. Here, we propose a simple heuristic for designing a point spread function (PSF) that allows for precise measurement of the distance between two emitters. We discover that there are two types of PSFs that achieve high performance for resolving emitters in 3D, as quantified by the Cramér-Rao bounds for estimating the separation between two closely spaced emitters. One PSF is very similar to the existing Tetrapod PSFs; the other is a rotating single-spot PSF, which we call the crescent PSF. The latter exhibits excellent performance for localizing single emitters throughout a 1-µm focal volume (localization precisions of 7.3 nm in x , 7.7 nm in y , and 18.3 nm in z using 1000 detected photons), and it distinguishes between one and two closely spaced emitters with superior accuracy (25-53% lower error rates than the best-performing Tetrapod PSF, averaged throughout a 1-µm focal volume). Our study provides additional insights into optimal strategies for encoding 3D spatial information into optical PSFs.
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Inverse designed extended depth of focus meta-optics for broadband imaging in the visible
Abstract We report an inverse-designed, high numerical aperture (∼0.44), extended depth of focus (EDOF) meta-optic, which exhibits a lens-like point spread function (PSF). The EDOF meta-optic maintains a focusing efficiency comparable to that of a hyperboloid metalens throughout its depth of focus. Exploiting the extended depth of focus and computational post processing, we demonstrate broadband imaging across the full visible spectrum using a 1 mm, f/1 meta-optic. Unlike other canonical EDOF meta-optics, characterized by phase masks such as a log-asphere or cubic function, our design exhibits a highly invariant PSF across ∼290 nm optical bandwidth, which leads to significantly improved image quality, as quantified by structural similarity metrics.
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- PAR ID:
- 10343713
- Date Published:
- Journal Name:
- Nanophotonics
- Volume:
- 11
- Issue:
- 11
- ISSN:
- 2192-8614
- Page Range / eLocation ID:
- 2531 to 2540
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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- Free Publicly Accessible Full Text
-
Accepted Manuscript
- Journal Article:
- https://doi.org/10.1515/nanoph-2021-0431
