skip to main content
US FlagAn official website of the United States government
dot gov icon
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
https lock icon
Secure .gov websites use HTTPS
A lock ( lock ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.


Title: Privacy-preserving logistic regression with secret sharing
Abstract Background Logistic regression (LR) is a widely used classification method for modeling binary outcomes in many medical data classification tasks. Researchers that collect and combine datasets from various data custodians and jurisdictions can greatly benefit from the increased statistical power to support their analysis goals. However, combining data from different sources creates serious privacy concerns that need to be addressed. Methods In this paper, we propose two privacy-preserving protocols for performing logistic regression with the Newton–Raphson method in the estimation of parameters. Our proposals are based on secure Multi-Party Computation (MPC) and tailored to the honest majority and dishonest majority security settings. Results The proposed protocols are evaluated against both synthetic and real-world datasets in terms of efficiency and accuracy, and a comparison is made with the ordinary logistic regression. The experimental results demonstrate that the proposed protocols are highly efficient and accurate. Conclusions Our work introduces two iterative algorithms to enable the distributed training of a logistic regression model in a privacy-preserving manner. The implementation results show that our algorithms can handle large datasets from multiple sources.  more » « less
Award ID(s):
2027790
PAR ID:
10352888
Author(s) / Creator(s):
; ;
Date Published:
Journal Name:
BMC Medical Informatics and Decision Making
Volume:
22
Issue:
1
ISSN:
1472-6947
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
More Like this
  1. We consider the differentially private sparse learning problem, where the goal is to estimate the underlying sparse parameter vector of a statistical model in the high-dimensional regime while preserving the privacy of each training example. We propose a generic differentially private iterative gradient hard threshoding algorithm with a linear convergence rate and strong utility guarantee. We demonstrate the superiority of our algorithm through two specific applications: sparse linear regression and sparse logistic regression. Specifically, for sparse linear regression, our algorithm can achieve the best known utility guarantee without any extra support selection procedure used in previous work [Kifer et al., 2012]. For sparse logistic regression, our algorithm can obtain the utility guarantee with a logarithmic dependence on the problem dimension. Experiments on both synthetic data and real world datasets verify the effectiveness of our proposed algorithm. 
    more » « less
  2. Stochastic gradient Langevin dynamics (SGLD) and stochastic gradient Hamiltonian Monte Carlo (SGHMC) are two popular Markov Chain Monte Carlo (MCMC) algorithms for Bayesian inference that can scale to large datasets, allowing to sample from the posterior distribution of the parameters of a statistical model given the input data and the prior distribution over the model parameters. However, these algorithms do not apply to the decentralized learning setting, when a network of agents are working collaboratively to learn the parameters of a statistical model without sharing their individual data due to privacy reasons or communication constraints. We study two algorithms: Decentralized SGLD (DE-SGLD) and Decentralized SGHMC (DE-SGHMC) which are adaptations of SGLD and SGHMC methods that allow scaleable Bayesian inference in the decentralized setting for large datasets. We show that when the posterior distribution is strongly log-concave and smooth, the iterates of these algorithms converge linearly to a neighborhood of the target distribution in the 2-Wasserstein distance if their parameters are selected appropriately. We illustrate the efficiency of our algorithms on decentralized Bayesian linear regression and Bayesian logistic regression problems 
    more » « less
  3. Big Data empowers the farming community with the information needed to optimize resource usage, increase productivity, and enhance the sustainability of agricultural practices. The use of Big Data in farming requires the collection and analysis of data from various sources such as sensors, satellites, and farmer surveys. While Big Data can provide the farming community with valuable insights and improve efficiency, there is significant concern regarding the security of this data as well as the privacy of the participants. Privacy regulations, such as the European Union’s General Data Protection Regulation (GDPR), the EU Code of Conduct on agricultural data sharing by contractual agreement, and the proposed EU AI law, have been created to address the issue of data privacy and provide specific guidelines on when and how data can be shared between organizations. To make confidential agricultural data widely available for Big Data analysis without violating the privacy of the data subjects, we consider privacy-preserving methods of data sharing in agriculture. Synthetic data that retains the statistical properties of the original data but does not include actual individuals’ information provides a suitable alternative to sharing sensitive datasets. Deep learning-based synthetic data generation has been proposed for privacy-preserving data sharing. However, there is a lack of compliance with documented data privacy policies in such privacy-preserving efforts. In this study, we propose a novel framework for enforcing privacy policy rules in privacy-preserving data generation algorithms. We explore several available agricultural codes of conduct, extract knowledge related to the privacy constraints in data, and use the extracted knowledge to define privacy bounds in a privacy-preserving generative model. We use our framework to generate synthetic agricultural data and present experimental results that demonstrate the utility of the synthetic dataset in downstream tasks. We also show that our framework can evade potential threats, such as re-identification and linkage issues, and secure data based on applicable regulatory policy rules. 
    more » « less
  4. Nikolski, Macha (Ed.)
    Abstract MotivationGenome-wide association studies (GWAS) benefit from the increasing availability of genomic data and cross-institution collaborations. However, sharing data across institutional boundaries jeopardizes medical data confidentiality and patient privacy. While modern cryptographic techniques provide formal secure guarantees, the substantial communication and computational overheads hinder the practical application of large-scale collaborative GWAS. ResultsThis work introduces an efficient framework for conducting collaborative GWAS on distributed datasets, maintaining data privacy without compromising the accuracy of the results. We propose a novel two-step strategy aimed at reducing communication and computational overheads, and we employ iterative and sampling techniques to ensure accurate results. We instantiate our approach using logistic regression, a commonly used statistical method for identifying associations between genetic markers and the phenotype of interest. We evaluate our proposed methods using two real genomic datasets and demonstrate their robustness in the presence of between-study heterogeneity and skewed phenotype distributions using a variety of experimental settings. The empirical results show the efficiency and applicability of the proposed method and the promise for its application for large-scale collaborative GWAS. Availability and implementationThe source code and data are available at https://github.com/amioamo/TDS. 
    more » « less
  5. While embracing various machine learning techniques to make effective decisions in the big data era, preserving the privacy of sensitive data poses significant challenges. In this paper, we develop a privacy-preserving distributed machine learning algorithm to address this issue. Given the assumption that each data provider owns a dataset with different sample size, our goal is to learn a common classifier over the union of all the local datasets in a distributed way without leaking any sensitive information of the data samples. Such an algorithm needs to jointly consider efficient distributed learning and effective privacy preservation. In the proposed algorithm, we extend stochastic alternating direction method of multipliers (ADMM) in a distributed setting to do distributed learning. For preserving privacy during the iterative process, we combine differential privacy and stochastic ADMM together. In particular, we propose a novel stochastic ADMM based privacy-preserving distributed machine learning (PS-ADMM) algorithm by perturbing the updating gradients, that provide differential privacy guarantee and have a low computational cost. We theoretically demonstrate the convergence rate and utility bound of our proposed PS-ADMM under strongly convex objective. Through our experiments performed on real-world datasets, we show that PS-ADMM outperforms other differentially private ADMM algorithms under the same differential privacy guarantee. 
    more » « less