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   Kubernetes, an open-source container orchestration platform, has been widely adopted by cloud service providers (CSPs) for its advantages in simplifying container deployment, scalability and scheduling. Networking is one of the central components of Kubernetes, providing connectivity between different pods (group of containers) both within the same host and across hosts. To bootstrap Kubernetes networking, the Container Network Interface (CNI) provides a unified interface for the interaction between container runtimes. There are several CNI implementations, available as open-source ‘CNI plugins’. While they differ in functionality and performance, it is a challenge for a cloud provider to differentiate and choose the appropriate plugin for their environment. In this paper, we compare the various open source CNI plugins available from the community, qualitatively and through detailed quantitative measurements. With our experimental evaluation, we analyze the overheads and bottlenecks for each CNI plugin, as a result of the network model it implements, interaction with the host network protocol stack and the network policies implemented in iptables rules. The choice of the CNI plugin may also be based on whether intra-host or inter-host communication dominates. 

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5. CHESPA/CHESCA-SPARKY: automated NMR data analysis plugins for SPARKY to map protein allostery

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   Abstract Motivation Correlated Nuclear Magnetic Resonance (NMR) chemical shift changes identified through the CHEmical Shift Projection Analysis (CHESPA) and CHEmical Shift Covariance Analysis (CHESCA) reveal pathways of allosteric transitions in biological macromolecules. To address the need for an automated platform that implements CHESPA and CHESCA and integrates them with other NMR analysis software packages, we introduce here integrated plugins for NMRFAM-SPARKY that implement the seamless detection and visualization of allosteric networks. Availability and implementation CHESCA-SPARKY and CHESPA-SPARKY are available in the latest version of NMRFAM-SPARKY from the National Magnetic Resonance Facility at Madison (http://pine.nmrfam.wisc.edu/download_packages.html), the NMRbox Project (https://nmrbox.org) and to subscribers to the SBGrid (https://sbgrid.org). The assigned spectra involved in this study and tutorial videos using this dataset are available at https://sites.google.com/view/chescachespa-sparky. Supplementary information Supplementary data are available at Bioinformatics Online. 

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