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Title: Molecular interactions of melatonin with lipid rafts
Biological membranes are composed of a lipid bilayer with a heterogeneous structure and complex dynamics, both of which can be modulated by the presence of melatonin. The lateral heterogeneities in lipid bilayers, also known as lipid rafts, have unique molecular interactions with melatonin, which we review here. Specifically, we discuss the molecular-level, physicochemical influences of melatonin on dynamics of lipid rafts and their structural properties, including melatonin’s propensity to preserve the structural integrity of lipid rafts at different length scales, as revealed through a range of experimental techniques and theoretical approaches.  more » « less
Award ID(s):
2219289
NSF-PAR ID:
10401399
Author(s) / Creator(s):
; ;
Date Published:
Journal Name:
Melatonin Research
Volume:
5
Issue:
2
ISSN:
2641-0281
Page Range / eLocation ID:
101 to 113
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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