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Abstract The central nervous system’s (CNS) dopaminergic system dysfunction has been linked to neurological illnesses like schizophrenia and Parkinson’s disease. As a result, sensitive and selective detection of dopamine is critical for the early diagnosis of illnesses associated with aberrant dopamine levels. In this research, we have investigated the performance of electrochemical screen-printed sensors for different concentrations of dopamine detection using graphene-based conductive PEDOT: PSS(G-PEDOT: PSS) and Polyaniline(G-PANI) inks on the working electrode and compared the sensitivity. SEM characterization technique has been performed to visualize the microstructures of the proposed inks. We have investigated cyclic voltammetry (CV) electrochemical techniques with ferri/ferrocyanide redox couple to assess the efficiency of the designed electrodes in detecting dopamine. G-PANI ink has shown to have better LOD and stability to detect dopamine with screen-printed electrodes. Further, we have also studied electrochemical analysis for the selective detection of dopamine without the interference of Ascorbic Acid (AA).
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Recent advances in the utilization of polyaniline in protein detection: a short review
Various reports have been published based on covalently attaching biomolecules to polyaniline (PANI). The functional groups connected to the surface of polymeric units determine the immobilization method as well as the method of detection. The present mini-review aims at covering recent advances in the field of protein binding and detection using PANI. Several proteins have been attached to the polymer using different immobilization techniques. The application of PANI in protein detection has also been discussed along with the future scope of these materials in diagnosis and detection.
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- Award ID(s):
- 2122044
- PAR ID:
- 10412198
- Date Published:
- Journal Name:
- RSC Advances
- Volume:
- 12
- Issue:
- 51
- ISSN:
- 2046-2069
- Page Range / eLocation ID:
- 32885 to 32897
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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- Free Publicly Accessible Full Text
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Accepted Manuscript1.0
- Journal Article:
- https://doi.org/10.1039/D2RA05893F
