We prove a single-value version of Reshetnyak’s theorem. Namely, if a non-constant map from a domain satisfies the estimate at almost every for some , and , then is discrete, the local index is positive in , and every neighborhood of a point of is mapped to a neighborhood of . Assuming this estimate for a fixed at every is equivalent to assuming that the map is -quasiregular, even if the choice of is different for each . Since the estimate also yields a single-value Liouville theorem, it hence appears to be a good pointwise definition of -quasiregularity. As a corollary of our single-value Reshetnyak’s theorem, we obtain a higher-dimensional version of the argument principle that played a key part in the solution to the Calderón problem.
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Tumor growth with nutrients: Regularity and stability
In this paper, we study a tumor growth model with nutrients. The model presents dynamic patch solutions due to the incompressibility of the tumor cells. We show that when the nutrients do not diffuse and the cells do not die, the tumor density exhibits regularizing dynamics thanks to an unexpected comparison principle. Using the comparison principle, we provide quantitative -contraction estimates and establish the -boundary regularity of the tumor patch. Furthermore, whenever the initial nutrient either lies entirely above or entirely below the critical value , we are able to give a complete characterization of the long-time behavior of the system. When is constant, we can even describe the dynamics of the full system in terms of some simpler nutrient-free and parameter-free model problems. These results are in sharp contrast to the observed behavior of the models either with nutrient diffusion or with death rate in tumor cells.
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- Award ID(s):
- 2153254
- PAR ID:
- 10412865
- Publisher / Repository:
- American Mathematical Society (AMS)
- Date Published:
- Journal Name:
- Communications of the American Mathematical Society
- Volume:
- 3
- Issue:
- 4
- ISSN:
- 2692-3688
- Page Range / eLocation ID:
- p. 166-208
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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