More Like this
Genetic and physical interactions between the organellar mechanosensitive ion channel homologs
MSL1, MSL2, and MSL3 reveal a role for inter‐organellar communication in plant development Abstract
Plant development requires communication on many levels, including between cells and between organelles within a cell. For example, mitochondria and plastids have been proposed to be sensors of environmental stress and to coordinate their responses. Here we present evidence for communication between mitochondria and chloroplasts during leaf and root development, based on genetic and physical interactions between three
Mechanosensitive channel of Small conductance‐ Like ( MSL) proteins from Arabidopsis thaliana. MSLproteins are Arabidopsishomologs of the bacterial Mechano sensitive channel of Small conductance (MscS), which relieves cellular osmotic pressure to protect against lysis during hypoosmotic shock. MSL1 localizes to the inner mitochondrial membrane, while MSL2 and MSL3 localize to the inner plastid membrane and are required to maintain plastid osmotic homeostasis during normal growth and development. In this study, we characterized the phenotypic effect of a genetic lesion in , both in wild type and in MSL1 msl2 msl3mutant backgrounds. msl1single mutants appear wild type for all phenotypes examined. The characteristic leaf rumpling in msl2 msl3double mutants was exacerbated in the msl1 msl2 msl3triple mutant. However, the introduction of the msl1lesion into the msl2 msl3mutant background suppressed other msl2 msl3mutant phenotypes, including ectopic callus formation, accumulation of superoxide and hydrogen peroxide in the shoot apical meristem, decreased root length, and reduced number of lateral roots. All thesemore »
Genetic contributions to dental dimensions in brown‐mantled tamarins (
Saguinus fuscicollis) and rhesus macaques ( Macaca mulatta) Abstract Objectives
The use of dental metrics in phylogenetic reconstructions of fossil primates assumes variation in tooth size is highly heritable. Quantitative genetic studies in humans and baboons have estimated high heritabilities for dental traits, providing a preliminary view of the variability of dental trait heritability in nonhuman primate species. To expand upon this view, the heritabilities and evolvabilities of linear dental dimensions are estimated in brown‐mantled tamarins (
) and rhesus macaques ( Saguinus fuscicollis ). Macaca mulatta Materials and methods
Quantitative genetic analyses were performed on linear dental dimensions collected from 302 brown‐mantled tamarins and 364 rhesus macaques. Heritabilities were estimated in SOLAR using pedigrees from each population, and evolvabilities were calculated manually.
Tamarin heritability estimates range from 0.19 to 0.99, and 25 of 26 tamarin estimates are significantly different from zero. Macaque heritability estimates range from 0.08 to 1.00, and 25 out of 28 estimates are significantly different from zero.
Dental dimensions are highly heritable in captive brown‐mantled tamarins and free‐ranging rhesus macaques. The range of heritability estimates in these populations is broadly similar to those of baboons and humans. Evolvability tends to increase with heritability, although evolvability is high relative to heritability in some dimensions. Estimating evolvability helps to contextualizemore »