Localized cytotoxic T cell–associated antigen 4 and antioxidant islet encapsulation alters macrophage signaling and induces regulatory and anergic T cells to enhance allograft survival

Barra, Jessie M.; Kozlovskaya, Veronika; Burnette, KaLia S.; Banerjee, Ronadip R.; Fraker, Christopher A.; Kharlampieva, Eugenia; Tse, Hubert M.

doi:10.1016/j.ajt.2023.01.007

A bstract The $$ T\overline{T} $$ T T ¯ deformation can be formulated as a dynamical change of coordinates. We establish and generalize this relation to curved spaces by coupling the undeformed theory to 2d gravity. For curved space the dynamical change of coordinates is supplemented by a dynamical Weyl transformation. We also sharpen the holographic correspondence to cutoff AdS 3 in multiple ways. First, we show that the action of the annular region between the cutoff surface and the boundary of AdS 3 is given precisely by the $$ T\overline{T} $$ T T ¯ operator integrated over either the cutoff surface or the asymptotic boundary. Then we derive dynamical coordinate and Weyl transformations directly from the bulk. Finally, we reproduce the flow equation for the deformed stress tensor from the cutoff geometry.

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