Multi-View Clustering (MVC) aims to find the cluster structure shared by multiple views of a particular dataset. Existing MVC methods mainly integrate the raw data from different views, while ignoring the high-level information. Thus, their performance may degrade due to the conflict between heterogeneous features and the noises existing in each individual view. To overcome this problem, we propose a novel Multi-View Ensemble Clustering (MVEC) framework to solve MVC in an Ensemble Clustering (EC) way, which generates Basic Partitions (BPs) for each view individually and seeks for a consensus partition among all the BPs. By this means, we naturally leverage the complementary information of multi-view data in the same partition space. Instead of directly fusing BPs, we employ the low-rank and sparse decomposition to explicitly consider the connection between different views and detect the noises in each view. Moreover, the spectral ensemble clustering task is also involved by our framework with a carefully designed constraint, making MVEC a unified optimization framework to achieve the final consensus partition. Experimental results on six real-world datasets show the efficacy of our approach compared with both MVC and EC methods.
Multi-view clustering by CPS-merge analysis with application to multimodal single-cell data
Multi-view data can be generated from diverse sources, by different technologies, and in multiple modalities. In various fields, integrating information from multi-view data has pushed the frontier of discovery. In this paper, we develop a new approach for multi-view clustering, which overcomes the limitations of existing methods such as the need of pooling data across views, restrictions on the clustering algorithms allowed within each view, and the disregard for complementary information between views. Our new method, called CPS-merge analysis , merges clusters formed by the Cartesian product of single-view cluster labels, guided by the principle of maximizing clustering stability as evaluated by CPS analysis. In addition, we introduce measures to quantify the contribution of each view to the formation of any cluster. CPS-merge analysis can be easily incorporated into an existing clustering pipeline because it only requires single-view cluster labels instead of the original data. We can thus readily apply advanced single-view clustering algorithms. Importantly, our approach accounts for both consensus and complementary effects between different views, whereas existing ensemble methods focus on finding a consensus for multiple clustering results, implying that results from different views are variations of one clustering structure. Through experiments on single-cell datasets, we demonstrate that our approach frequently outperforms other state-of-the-art methods.
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- Award ID(s):
- 2013905
- NSF-PAR ID:
- 10437321
- Editor(s):
- Alber, Mark
- Date Published:
- Journal Name:
- PLOS Computational Biology
- Volume:
- 19
- Issue:
- 4
- ISSN:
- 1553-7358
- Page Range / eLocation ID:
- e1011044
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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- Free Publicly Accessible Full Text
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Accepted Manuscript1.0
- Journal Article:
- https://doi.org/10.1371/journal.pcbi.1011044
