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Abstract Development of paper-based microfluidic devices that perform colorimetric measurements requires quantitative image analysis. Because the design geometries of paper-based microfluidic devices are not standardized, conventional methods for performing batch measurements of regularly spaced areas of signal intensity, such as those for well plates, cannot be used to quantify signal from most of these devices. To streamline the device development process, we have developed an open-source program called ColorScan that can automatically recognize and measure signal-containing zones from images of devices, regardless of output zone geometry or spatial arrangement. This program, which measures color intensity with the same accuracy as standard manual approaches, can rapidly process scanned device images, simultaneously measure identified output zones, and effectively manage measurement results to eliminate requirements for time-consuming and user-dependent image processing procedures.
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Fit As a Diagnostic Tool: An Analytic Review of Approaches to Measure Correspondence Between Technical and Organizational Architectures
Abstract Standardized design approaches such as those embodied by concurrent design facilities have many benefits, such as increased efficiency of the design process, but may also have hidden costs. Specifically, when their standardized organizational decomposition is a poor fit for the particular design problem, important design trades might be missed or poor decisions made. Before we can understand how this lack of fit impacts the design process, we must be able to empirically observe and measure it. To that end, this paper identifies measures of “fit” from the literature along with attributes likely to impact design process performance, then evaluates the measures to determine how well the measures can detect and diagnose potential issues. The results provide comparative insights into the capabilities of existing fit measures, and also build guidance for how the systems engineering and design community can use insights from the “fit” literature to inform process improvement.
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- Award ID(s):
- 2125677
- PAR ID:
- 10448612
- Date Published:
- Journal Name:
- Journal of Mechanical Design
- Volume:
- 144
- Issue:
- 12
- ISSN:
- 1050-0472
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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- Free Publicly Accessible Full Text
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Accepted Manuscript1.0
- Journal Article:
- https://doi.org/10.1115/1.4055150
