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  • Network architecture and sex chromosome turnovers: Do epistatic interactions shape patterns of sex chromosome replacement?
Title: Network architecture and sex chromosome turnovers: Do epistatic interactions shape patterns of sex chromosome replacement?
Abstract Recent studies have revealed an astonishing diversity of sex chromosomes in many vertebrate lineages, prompting questions about the mechanisms of sex chromosome turnover. While there is considerable population genetic theory about the evolutionary forces promoting sex chromosome replacement, this theory has not yet been integrated with our understanding of the molecular and developmental genetics of sex determination. Here, we review recent data to examine four questions about how the structure of gene networks influences the evolution of sex determination. We argue that patterns of epistasis, arising from the structure of genetic networks, may play an important role in regulating the rates and patterns of sex chromosome replacement.  more » « less
Award ID(s):
1830753
PAR ID:
10450915
Author(s) / Creator(s):
 ;  ;  ;  
Publisher / Repository:
Wiley Blackwell (John Wiley & Sons)
Date Published:
Journal Name:
BioEssays
Volume:
43
Issue:
3
ISSN:
0265-9247
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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