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Abstract An application of multi‐component milling is described to achieve a decolorization by dismantling the orange‐red zwitterionic cocrystal (PDA)∙(APAP) (wherePDA= 2,4‐pyridinedicarboxylic acid,APAP= acetaminophen) usingn,n′‐BPE(BPE=trans‐1,2‐bis(n‐pyridylethylene and forn=n′ = 3 or 4). Each ofn,n′‐BPEforms a colorless hydrogen‐bonded cocrystal withPDA.
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Absolute stereochemical determination of 1,2‐diols via complexation with dinaphthyl borinic acid
Abstract Rapid derivatization of chiral 1,2‐diols with dinaphthyl borinic acid (DBA) leads to a cyclic boronate, enabling the absolute stereochemical prediction via exciton‐coupled circular dichroic (ECCD) of the naphthyl groups. Aryl‐ and alkyl‐substituted 1,2‐diols derivatized withDBAyield a predictable ECCD, which is also in agreement with theoretical predictions derived from computationally minimized structures.
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- Award ID(s):
- 1856335
- PAR ID:
- 10458063
- Publisher / Repository:
- Wiley Blackwell (John Wiley & Sons)
- Date Published:
- Journal Name:
- Chirality
- Volume:
- 32
- Issue:
- 6
- ISSN:
- 0899-0042
- Page Range / eLocation ID:
- p. 817-823
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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