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Title: Ups and downs of lysosomal pH: conflicting roles of LAMP proteins?
The acidic pH of lysosomes is critical for catabolism in eukaryotic cells and is altered in neurodegenerative disease including Alzheimer and Parkinson. Recent reports using Drosophila and mammalian cell culture systems have identified novel and, at first sight, conflicting roles for the lysosomal associated membrane proteins (LAMPs) in the regulation of the endolysosomal system.  more » « less
Award ID(s):
1714996
PAR ID:
10476349
Author(s) / Creator(s):
; ;
Publisher / Repository:
Taylor & Francis Group
Date Published:
Journal Name:
Autophagy
ISSN:
1554-8627
Page Range / eLocation ID:
1 to 4
Subject(s) / Keyword(s):
Alzheimer LAMP proteins lysosome Parkinson pH Autophagy
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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