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Title: Controlled Synthesis and Properties of Poly( l -homoserine)
We report preparation of a new water soluble, non-ionic homopolypeptide poly(L-homoserine) as well as poly(L-homoserine) block copolymers with controllable segment lengths. The conformational preferences of poly(L-homoserine) were also determined in both the solid-state and in solution. Poly(L-homoserine) is soluble in water and adopts a disordered conformation that makes it a promising addition to the small class of non-ionic, water soluble homopolypeptides with potential for development for applications in biology. Toward this goal, a poly(L-homoserine) containing block copolypeptide was prepared and found to assemble into micro- and nanoscale vesicles in water.  more » « less
Award ID(s):
1904431
PAR ID:
10488931
Author(s) / Creator(s):
;
Publisher / Repository:
American Chemical Society
Date Published:
Journal Name:
ACS Macro Letters
Volume:
12
Issue:
4
ISSN:
2161-1653
Page Range / eLocation ID:
518 to 522
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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