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  • Widespread dissolved inorganic carbon-modifying toolkits in genomes of autotrophic Bacteria and Archaea and how they are likely to bridge supply from the environment to demand by autotrophic pathways
Title: Widespread dissolved inorganic carbon-modifying toolkits in genomes of autotrophic Bacteria and Archaea and how they are likely to bridge supply from the environment to demand by autotrophic pathways
ABSTRACT Using dissolved inorganic carbon (DIC) as a major carbon source, as autotrophs do, is complicated by the bedeviling nature of this substance. Autotrophs using the Calvin-Benson-Bassham cycle (CBB) are known to make use of a toolkit comprised of DIC transporters and carbonic anhydrase enzymes (CA) to facilitate DIC fixation. This minireview provides a brief overview of the current understanding of how toolkit function facilitates DIC fixation inCyanobacteriaand someProteobacteriausing the CBB and continues with a survey of the DIC toolkit gene presence in organisms using different versions of the CBB and other autotrophic pathways (reductive citric acid cycle, Wood-Ljungdahl pathway, hydroxypropionate bicycle, hydroxypropionate-hydroxybutyrate cycle, and dicarboxylate-hydroxybutyrate cycle). The potential function of toolkit gene products in these organisms is discussed in terms of CO2and HCO3−supply from the environment and demand by the autotrophic pathway. The presence of DIC toolkit genes in autotrophic organisms beyond those using the CBB suggests the relevance of DIC metabolism to these organisms and provides a basis for better engineering of these organisms for industrial and agricultural purposes.  more » « less
Award ID(s):
1952676
PAR ID:
10494308
Author(s) / Creator(s):
; ;
Editor(s):
Bose, Arpita
Publisher / Repository:
American Society for Microbiology
Date Published:
Journal Name:
Applied and Environmental Microbiology
Volume:
90
Issue:
2
ISSN:
0099-2240
Subject(s) / Keyword(s):
autotroph carbon fixation carbonic anhydrase carbon dioxide concentrating mechanism
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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