Structured illumination microscopy (SIM) reconstructs optically-sectioned images of a sample from multiple spatially-patterned wide-field images, but the traditional single non-patterned wide-field images are more inexpensively obtained since they do not require generation of specialized illumination patterns. In this work, we translated wide-field fluorescence microscopy images to optically-sectioned SIM images by a Pix2Pix conditional generative adversarial network (cGAN). Our model shows the capability of both 2D cross-modality image translation from wide-field images to optical sections, and further demonstrates potential to recover 3D optically-sectioned volumes from wide-field image stacks. The utility of the model was tested on a variety of samples including fluorescent beads and fresh human tissue samples.
A new class of optically addressable dielectric elastomer actuators is presented that utilize the photoconductivity of semiconducting zinc oxide nanowires to create optically switchable and stretchable electrical channels.
more » « less- Award ID(s):
- 2011754
- PAR ID:
- 10500018
- Publisher / Repository:
- Royal Society of Chemistry
- Date Published:
- Journal Name:
- Materials Horizons
- Volume:
- 9
- Issue:
- 12
- ISSN:
- 2051-6347
- Page Range / eLocation ID:
- 3110 to 3117
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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