Caratheodory’s theorem says that any point in the convex hull of a set $$P$$ in $R^d$ is in the convex hull of a subset $P'$ of $$P$$ such that $$|P'| \le d + 1$$. For some sets P, the upper bound d + 1 can be improved. The best upper bound for P is known as the Caratheodory number [2, 15, 17]. In this paper, we study a computational problem of finding the smallest set $P'$ for a given set $$P$$ and a point $$p$$. We call the size of this set $P'$, the Caratheodory number of a point p or CNP. We show that the problem of deciding the Caratheodory number of a point is NP-hard. Furthermore, we show that the problem is k-LDT-hard. We present two algorithms for computing a smallest set $P'$, if CNP= 2,3. Bárány [1] generalized Caratheodory’s theorem by using d+1 sets (colored sets) such that their convex hulls intersect. We introduce a Colorful Caratheodory number of a point or CCNP which can be smaller than d+1. Then we extend our results for CNP to CCNP.
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Biomolecular interactions studied by low-field NMR using SABRE hyperpolarization
Nuclear spin hyperpolarization by parahydrogen enables the measurement of biomolecular interactions without the need for a superconducting or permanent magnet. Observed is a fluorine signal of a purpose-designed reporter ligand for a target protein.
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- Award ID(s):
- 1900406
- PAR ID:
- 10558123
- Publisher / Repository:
- Royal Society of Chemistry
- Date Published:
- Journal Name:
- Chemical Science
- Volume:
- 14
- Issue:
- 37
- ISSN:
- 2041-6520
- Page Range / eLocation ID:
- 10258 to 10263
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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