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Summary Scenario‐based model predictive control (MPC) methods can mitigate the conservativeness inherent to open‐loop robust MPC. Yet, the scenarios are often generated offline based on worst‐case uncertainty descriptions obtaineda priori, which can in turn limit the improvements in the robust control performance. To this end, this paper presents a learning‐based, adaptive‐scenario‐tree model predictive control approach for uncertain nonlinear systems with time‐varying and/or hard‐to‐model dynamics. Bayesian neural networks (BNNs) are used to learn a state‐ and input‐dependent description of model uncertainty, namely the mismatch between a nominal (physics‐based or data‐driven) model of a system and its actual dynamics. We first present a new approach for training robust BNNs (RBNNs) using probabilistic Lipschitz bounds to provide a less conservative uncertainty quantification. Then, we present an approach to evaluate the credible intervals of RBNN predictions and determine the number of samples required for estimating the credible intervals given a credible level. The performance of RBNNs is evaluated with respect to that of standard BNNs and Gaussian process (GP) as a basis of comparison. The RBNN description of plant‐model mismatch with verified accurate credible intervals is employed to generate adaptive scenarios online for scenario‐based MPC (sMPC). The proposed sMPC approach with adaptive scenario tree can improve the robust control performance with respect to sMPC with a fixed, worst‐case scenario tree and with respect to an adaptive‐scenario‐based MPC (asMPC) using GP regression on a cold atmospheric plasma system. Furthermore, closed‐loop simulation results illustrate that robust model uncertainty learning via RBNNs can enhance the probability of constraint satisfaction of asMPC.
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This content will become publicly available on September 17, 2025
Nonlinear model predictive control of a conductance-based neuron model via data-driven forecasting
Abstract Objective. Precise control of neural systems is essential to experimental investigations of how the brain controls behavior and holds the potential for therapeutic manipulations to correct aberrant network states. Model predictive control, which employs a dynamical model of the system to find optimal control inputs, has promise for dealing with the nonlinear dynamics, high levels of exogenous noise, and limited information about unmeasured states and parameters that are common in a wide range of neural systems. However, the challenge still remains of selecting the right model, constraining its parameters, and synchronizing to the neural system.Approach. As a proof of principle, we used recent advances in data-driven forecasting to construct a nonlinear machine-learning model of a Hodgkin–Huxley type neuron when only the membrane voltage is observable and there are an unknown number of intrinsic currents.Main Results. We show that this approach is able to learn the dynamics of different neuron types and can be used with model predictive control (MPC) to force the neuron to engage in arbitrary, researcher-defined spiking behaviors.Significance.To the best of our knowledge, this is the first application of nonlinear MPC of a conductance-based model where there is only realistically limited information about unobservable states and parameters.
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- Award ID(s):
- 1942480
- PAR ID:
- 10570479
- Publisher / Repository:
- Journal of Neural Engineering
- Date Published:
- Journal Name:
- Journal of Neural Engineering
- Volume:
- 21
- Issue:
- 5
- ISSN:
- 1741-2560
- Page Range / eLocation ID:
- 056014
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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