skip to main content
US FlagAn official website of the United States government
dot gov icon
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
https lock icon
Secure .gov websites use HTTPS
A lock ( lock ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.


This content will become publicly available on August 28, 2025

Title: The molecular basis for the increased stability of the FUS-LC fibril at the anionic membrane- and air–water interfaces
The backbone hydrogen bonds of a peptide assembly derived from FUS-LC gain excess stability at the anionic membrane-water and air–water interfaces due to distinctive interfacial solvation properties.  more » « less
Award ID(s):
2154804
PAR ID:
10591333
Author(s) / Creator(s):
; ; ;
Publisher / Repository:
Royal Society of Chemistry
Date Published:
Journal Name:
Chemical Science
Volume:
15
Issue:
34
ISSN:
2041-6520
Page Range / eLocation ID:
13788-13799
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
More Like this
  1. Abstract In this article, we introduce the “dwelling paradox” to explore how the state actively produces water insecurity for people experiencing homelessness in the Global North. We explain that the dwelling paradox is (1) produced by a modernist ideology of public service delivery that privileges water provision through private infrastructural connections in the home; (2) is reproduced by the welfare‐warfare state, which has increasingly weaponized public water facilities and criminalized body functions in public space; and (3) is actively contested by some houseless communities, who challenge hegemonic ideals of the “home”—and its water infrastructure—as a private, atomized space. In advancing a relational and spatial understanding of water insecurity, we use the dwelling paradox to illustrate how unhoused people are caught in a space of institutional entrapment that is forged by state power and amplified by anti‐homeless legislation. Such spaces of entrapment make it extremely difficult for unhoused people to achieve a safe, healthy, and thriving life—the basis of the human rights to water and sanitation. This article is categorized under:Human Water > Water Governance 
    more » « less
  2. Abstract As a key ingredient of batteries for electric vehicles (EVs), lithium plays a significant role in climate change mitigation, but lithium has considerable impacts on water and society across its life cycle. Upstream extraction methods—including open‐pit mining, brine evaporation, and novel direct lithium extraction (DLE)—and downstream processes present different impacts on both the quantity and quality of water resources, leading to water depletion and contamination. Regarding upstream extraction, it is critical for a comprehensive assessment of lithium's life cycle to include cumulative impacts related not only to freshwater, but also mineralized or saline groundwater, also known as brine. Legal frameworks have obscured social and ecological impacts by treating brine as a mineral rather than water in regulation of lithium extraction through brine evaporation. Analysis of cumulative impacts across the lifespan of lithium reveals not only water impacts in conventional open‐pit mining and brine evaporation, but also significant freshwater needs for DLE technologies, as well as burdens on fenceline communities related to wastewater in processing, chemical contaminants in battery manufacturing, water use for cooling in energy storage, and water quality hazards in recycling. Water analysis in lithium life cycle assessments (LCAs) tends to exclude brine and lack hydrosocial context on the environmental justice implications of water use by life cycle stage. New research directions might benefit from taking a more community‐engaged and cradle‐to‐cradle approach to lithium LCAs, including regionalized impact analysis of freshwater use in DLE, as well as wastewater pollution, cooling water, and recycling hazards from downstream processes. This article is categorized under:Human Water > Human WaterHuman Water > Water GovernanceHuman Water > Water as Imagined and RepresentedScience of Water > Water and Environmental Change 
    more » « less
  3. Abstract Centralized water infrastructure has, over the last century, brought safe and reliable drinking water to much of the world. But climate change, combined with aging and underfunded infrastructure, is increasingly testing the limits of—and reversing gains made by—this approach. To address these growing strains and gaps, we must assess and advance alternatives to centralized water provision and sanitation. The water literature is rife with examples of systems that are neither centralized nor networked, yet meet water needs of local communities in important ways, including: informal and hybrid water systems, decentralized water provision, community‐based water management, small drinking water systems, point‐of‐use treatment, small‐scale water vendors, and packaged water. Our work builds on these literatures by proposing a convergence approach that can integrate and explore the benefits and challenges of modular, adaptive, and decentralized (“MAD”) water provision and sanitation, often foregrounding important advances in engineering technology. We further provide frameworks to evaluate justice, economic feasibility, governance, human health, and environmental sustainability as key parameters of MAD water system performance. This article is categorized under:Engineering Water > Water, Health, and SanitationHuman Water > Water GovernanceEngineering Water > Sustainable Engineering of Water 
    more » « less
  4. Abstract Water consumption from electricity systems can be large, and it varies greatly by region. As electricity systems change, understanding the implications for water demand is important, given differential water availability. This letter presents regional water consumption and consumptive intensities for the United States electric grid by region using a 2014 base year, based on the 26 regions in the Environmental Protection Agency’s Emissions & Generation Resource Integrated Database. Estimates encompass operational (i.e. not embodied in fixed assets) water consumption from fuel extraction through conversion, calculated as the sum of induced water consumption for processes upstream of the point of generation (PoG) and water consumed at the PoG. Absolute water consumption and consumptive intensity is driven by thermal power plant cooling requirements. Regional consumption intensities vary by roughly a factor of 20. This variability is largely attributed to water consumption upstream of the PoG, particularly evaporation from reservoirs associated with hydroelectricity. Solar and wind generation, which are expected to continue to grow rapidly, consume very little water and could drive lower water consumption over time. As the electricity grid continues to change in response to policy, economic, and climatic drivers, understanding potential impacts on local water resources can inform changes. 
    more » « less
  5. Abstract Persistent overuse of water supplies from the Colorado River during recent decades has substantially depleted large storage reservoirs and triggered mandatory cutbacks in water use. The river holds critical importance to more than 40 million people and more than two million hectares of cropland. Therefore, a full accounting of where the river’s water goes en route to its delta is necessary. Detailed knowledge of how and where the river’s water is used can aid design of strategies and plans for bringing water use into balance with available supplies. Here we apply authoritative primary data sources and modeled crop and riparian/wetland evapotranspiration estimates to compile a water budget based on average consumptive water use during 2000–2019. Overall water consumption includes both direct human uses in the municipal, commercial, industrial, and agricultural sectors, as well as indirect water losses to reservoir evaporation and water consumed through riparian/wetland evapotranspiration. Irrigated agriculture is responsible for 74% of direct human uses and 52% of overall water consumption. Water consumed for agriculture amounts to three times all other direct uses combined. Cattle feed crops including alfalfa and other grass hays account for 46% of all direct water consumption. 
    more » « less