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For the treatment of chronic neuropathic diseases, long-term behavior study of the patient is very important. The behavior study is performed using neural stimulation and simultaneously recording the response from the neural cells. Headstage-based neuromodulation device has become one of the popular methods for neural stimulation in recent times. In this work, a wirelessly powered system is presented that provides constant power to a headstage based optogenetic stimulator, which includes a receiver (RX) coil, a rectifier, and an mm-sized light-emitting-diode (LED). A multi-layered transmitter (TX) coil is designed to provide uniform power transmission over the 20.7 cm × 14 cm mouse behavioral cage area. A maximum of ~49% efficiency is achieved using the proposed system at 3 cm distance through the air media at 13.56 MHz operating frequency. The proposed system uses less number of headstage resonators on the 3-D printed light-weight headstage which is able to achieve higher efficiency compared to the other state-of-the-art.
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This content will become publicly available on January 1, 2026
Computational Vector Stimulation for Spatially Targeted, Low-Latency Adaptive Neuromodulation With Common-Mode Artifact Suppression
This paper presents a technique for achieving spatially targeted neural stimulation with suppression of driver nonideality-induced common-mode (CM) artifact in low-latency closed-loop neuromodulation applications. The proposed approach utilizes computationally guided concurrent stimulation across multiple electrodes to achieve spatial selectivity in stimulation. The proposed architecture supports flexible storage of multiple, precomputed vector stimulation patterns in integrated memory. A selected stimulation pattern can be quickly accessed and administered in response to decoded neural activity. Additionally, a combination of the stimulator circuit architecture and mixed-signal current imbalance compensation techniques effectively suppress CM artifacts to below 50 mV. These techniques are demonstrated in a 180 nm HV CMOS test-chip containing 46 stimulation drivers of 26 V compliance and validated through a combination of bench, saline, and in vivo tests.
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- Award ID(s):
- 2317764
- PAR ID:
- 10613045
- Publisher / Repository:
- IEEE
- Date Published:
- Journal Name:
- IEEE Transactions on Circuits and Systems I: Regular Papers
- ISSN:
- 1549-8328
- Page Range / eLocation ID:
- 1 to 13
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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