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Abstract Human mobility is fundamental to a range of applications including epidemic control, urban planning, and traffic engineering. While laws governing individual movement trajectories and population flows across locations have been extensively studied, the predictability of population-level mobility during the COVID-19 pandemic driven by specific activities such as work, shopping, and recreation remains elusive. Here we analyze mobility data for six place categories at the US county level from 2020 February 15 to 2021 November 23 and measure how the predictability of these mobility metrics changed during the COVID-19 pandemic. We quantify the time-varying predictability in each place category using an information-theoretic metric, permutation entropy. We find disparate predictability patterns across place categories over the course of the pandemic, suggesting differential behavioral changes in human activities perturbed by disease outbreaks. Notably, predictability change in foot traffic to residential locations is mostly in the opposite direction to other mobility categories. Specifically, visits to residences had the highest predictability during stay-at-home orders in March 2020, while visits to other location types had low predictability during this period. This pattern flipped after the lifting of restrictions during summer 2020. We identify four key factors, including weather conditions, population size, COVID-19 case growth, and government policies, and estimate their nonlinear effects on mobility predictability. Our findings provide insights on how people change their behaviors during public health emergencies and may inform improved interventions in future epidemics.
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This content will become publicly available on April 29, 2026
Behavior-driven forecasts of neighborhood-level COVID-19 spread in New York City
The COVID-19 pandemic in New York City (NYC) was characterized by marked disparities in disease burdens across neighborhoods. Accurate neighborhood-level forecasts are critical for planning more equitable resource allocation to reduce health inequalities; however, such spatially high-resolution forecasts remain scarce in operational use. In this study, we analyze aggregated foot traffic data derived from mobile devices to measure the connectivity among 42 NYC neighborhoods driven by various human activities such as dining, shopping, and entertainment. Using real-world time-varying contact patterns in different place categories, we develop a parsimonious behavior-driven epidemic model that incorporates population mixing, indoor crowdedness, dwell time, and seasonality of virus transmissibility. We fit this model to neighborhood-level COVID-19 case data in NYC and further couple this model with a data assimilation algorithm to generate short-term forecasts of neighborhood-level COVID-19 cases in 2020. We find differential contact patterns and connectivity between neighborhoods driven by different human activities. The behavior-driven model supports accurate modeling of neighborhood-level SARS-CoV-2 transmission throughout 2020. In the best-fitting model, we estimate that the force of infection (FOI) in indoor settings increases sublinearly with crowdedness and dwell time. Retrospective forecasting demonstrates that this behavior-driven model generates improved short-term forecasts in NYC neighborhoods compared to several baseline models. Our findings indicate that aggregated foot-traffic data for routine human activities can support neighborhood-level COVID-19 forecasts in NYC. This behavior-driven model may be adapted for use with other respiratory pathogens sharing similar transmission routes.
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- Award ID(s):
- 2229605
- PAR ID:
- 10616833
- Editor(s):
- Ben-Nun, Michal
- Publisher / Repository:
- PLoS
- Date Published:
- Journal Name:
- PLOS Computational Biology
- Volume:
- 21
- Issue:
- 4
- ISSN:
- 1553-7358
- Page Range / eLocation ID:
- e1012979
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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