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Abstract An extremely rapid process for self‐assembling well‐ordered, nano, and microparticle monolayers via a novel aerosolized method is presented. The novel technique can reach monolayer self‐assembly rates as high as 268 cm2min−1from a single aerosolizing source and methods to reach faster monolayer self‐assembly rates are outlined. A new physical mechanism describing the self‐assembly process is presented and new insights enabling high‐efficiency nanoparticle monolayer self‐assembly are developed. In addition, well‐ordered monolayer arrays from particles of various sizes, surface functionality, and materials are fabricated. This new technique enables a 93× increase in monolayer self‐assembly rates compared to the current state of the art and has the potential to provide an extremely low‐cost option for submicron nanomanufacturing.
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This content will become publicly available on July 23, 2026
Applications of enhanced sampling methods to biomolecular self-assembly: a review
Abstract This review article discusses some common enhanced sampling methods in relation to the process of self-assembly of biomolecules. An introduction to self-assembly and its challenges is covered followed by a brief overview of the methods and analysis for replica-exchange molecular dynamics, umbrella sampling, metadynamics, and machine learning based techniques. Applications of select methods towards peptides, proteins, polymers, and nucleic acids are discussed. Finally, a short discussion of the future directions of some of these methods is provided.
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- Award ID(s):
- 1654325
- PAR ID:
- 10629606
- Publisher / Repository:
- IOP
- Date Published:
- Journal Name:
- Journal of Physics: Condensed Matter
- Volume:
- 37
- Issue:
- 30
- ISSN:
- 0953-8984
- Page Range / eLocation ID:
- 303001
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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