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Trapped-Ion (TI) technology offers potential breakthroughs for Noisy Intermediate Scale Quantum (NISQ) computing. TI qubits offer extended coherence times and high gate fidelity, making them appealing for large-scale NISQ computers. Constructing such computers demands a distributed architecture connecting Quantum Charge Coupled Devices (QCCDs) via quantum matter-links and photonic switches. However, current distributed TI NISQ computers face hardware and system challenges. Entangling qubits across a photonic switch introduces significant latency, while existing compilers generate suboptimal mappings due to their unawareness of the interconnection topology. In this paper, we introduce TITAN, a large-scale distributed TI NISQ computer, which employs an innovative photonic interconnection design to reduce entanglement latency and an advanced partitioning and mapping algorithm to optimize matter-link communications. Our evaluations show that TITAN greatly enhances quantum application performance by 56.6% and fidelity by 19.7% compared to existing systems. 

This paper presents \textit{OFHE}, an electro-optical accelerator designed to process Discretized TFHE (DTFHE) operations, which encrypt multi-bit messages and support homomorphic multiplications, lookup table operations and full-domain functional bootstrappings. While DTFHE is more efficient and versatile than other fully homomorphic encryption schemes, it requires 32-, 64-, and 128-bit polynomial multiplications, which can be time-consuming. Existing TFHE accelerators are not easily upgradable to support DTFHE operations due to limited datapaths, a lack of datapath bit-width reconfigurability, and power inefficiencies when processing FFT and inverse FFT (IFFT) kernels. Compared to prior TFHE accelerators, OFHE addresses these challenges by improving the DTFHE operation latency by 8.7\%, the DTFHE operation throughput by $$57\%$$, and the DTFHE operation throughput per Watt by $$94\%$$. 

We propose a circuit-level backdoor attack, QTrojan, against Quantum Neural Networks (QNNs) in this paper. QTrojan is implemented by a few quantum gates inserted into the variational quantum circuit of the victim QNN. QTrojan is much stealthier than a prior Data-Poisoning-based Backdoor Attack (DPBA) since it does not embed any trigger in the inputs of the victim QNN or require access to original training datasets. Compared to a DPBA, QTrojan improves the clean data accuracy by 21% and the attack success rate by 19.9%.