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In the face of the unprecedented COVID-19 pandemic, various government-led initiatives and individual actions (e.g., lockdowns, social distancing, and masking) have resulted in diverse pandemic experiences. This study aims to explore these varied experiences to inform more proactive responses for future public health crises. Employing a novel “big-thick” data approach, we analyze and compare key pandemic-related topics that have been disseminatedtothe public through newspapers with those collectedfromthe public via interviews. Specifically, we utilized 82,533 U.S. newspaper articles from January 2020 to December 2021 and supplemented this “big” dataset with “thick” data from interviews and focus groups for topic modeling. Identified key topics were contextualized, compared and visualized at different scales to reveal areas of convergence and divergence. We found seven key topics from the “big” newspaper dataset, providing a macro-level view that covers public health, policies and economics. Conversely, three divergent topics were derived from the “thick” interview data, offering a micro-level view that focuses more on individuals’ experiences, emotions and concerns. A notable finding is the public’s concern about the reliability of news information, suggesting the need for further investigation on the impacts of mass media in shaping the public’s perception and behavior. Overall, by exploring the convergence and divergence in identified topics, our study offers new insights into the complex impacts of the pandemic and enhances our understanding of key issues both disseminated to and resonating with the public, paving the way for further health communication and policy-making. 

Within the geo-simulation research domain, micro-simulation and agent-based modeling often require the creation of synthetic populations. Creating such data is a time-consuming task and often lacks social networks, which are crucial for studying human interactions (e.g., disease spread, disaster response) while at the same time impacting decision-making. We address these challenges by introducing a Python based method that uses the open data including that from 2020 U.S. Census data to generate a large-scale realistic geographically explicit synthetic population for America’s 50 states and Washington D.C. along with the stylized social networks (e.g., home, work and schools). The resulting synthetic population can be utilized within various geo-simulation approaches (e.g., agent-based modeling), exploring the emergence of complex phenomena through human interactions and further fostering the study of urban digital twins. 

Human mobility data science using trajectories or check-ins of individuals has many applications. Recently, we have seen a plethora of research efforts that tackle these applications. However, research progress in this field is limited by a lack of large and representative datasets. The largest and most commonly used dataset of individual human trajectories captures fewer than 200 individuals, while datasets of individual human check-ins capture fewer than 100 check-ins per city per day. Thus, it is not clear if findings from the human mobility data science community would generalize to large populations. Since obtaining massive, representative, and individual-level human mobility data is hard to come by due to privacy considerations, the vision of this work is to embrace the use of data generated by large-scale socially realistic microsimulations. Informed by both real data and leveraging social and behavioral theories, massive spatially explicit microsimulations may allow us to simulate entire megacities at the person level. The simulated worlds, which do not capture any identifiable personal information, allow us to perform “in silico” experiments using the simulated world as a sandbox in which we have perfect information and perfect control without jeopardizing the privacy of any actual individual. In silico experiments have become commonplace in other scientific domains such as chemistry and biology, permitting experiments that foster the understanding of concepts without any harm to individuals. This work describes challenges and opportunities for leveraging massive and realistic simulated alternate worlds for in silico human mobility data science. 

The COVID-19 pandemic has prompted an unprecedented global effort to understand and mitigate the spread of the SARS-CoV-2 virus. In this study, we present a comprehensive analysis of COVID-19 in Western New York (WNY), integrating individual patient-level genomic sequencing data with a spatially informed agent-based disease Susceptible-Exposed-Infectious-Recovered (SEIR) computational model. The integration of genomic and spatial data enables a multi-faceted exploration of the factors influencing the transmission patterns of COVID-19, including genetic variations in the viral genomes, population density, and movement dynamics in New York State (NYS). Our genomic analyses provide insights into the genetic heterogeneity of SARS-CoV-2 within a single lineage, at region-specific resolutions, while our population analyses provide models for SARS-CoV-2 lineage transmission. Together, our findings shed light on localized dynamics of the pandemic, revealing potential cross-county transmission networks. This interdisciplinary approach, bridging genomics and spatial modeling, contributes to a more comprehensive understanding of COVID-19 dynamics. The results of this study have implications for future public health strategies, including guiding targeted interventions and resource allocations to control the spread of similar viruses. 

Location-based social networks (LBSNs) have been studied extensively in recent years. However, utilizing real-world LBSN data sets yields several weaknesses: sparse and small data sets, privacy concerns, and a lack of authoritative ground-truth. To overcome these weaknesses, we leverage a large-scale LBSN simulation to create a framework to simulate human behavior and to create synthetic but realistic LBSN data based on human patterns of life. Such data not only captures the location of users over time but also their interactions via social networks. Patterns of life are simulated by giving agents (i.e., people) an array of “needs” that they aim to satisfy, e.g., agents go home when they are tired, to restaurants when they are hungry, to work to cover their financial needs, and to recreational sites to meet friends and satisfy their social needs. While existing real-world LBSN data sets are trivially small, the proposed framework provides a source for massive LBSN benchmark data that closely mimics the real-world. As such, it allows us to capture 100% of the (simulated) population without any data uncertainty, privacy-related concerns, or incompleteness. It allows researchers to see the (simulated) world through the lens of an omniscient entity having perfect data. Our framework is made available to the community. In addition, we provide a series of simulated benchmark LBSN data sets using different synthetic towns and real-world urban environments obtained from OpenStreetMap. The simulation software and data sets, which comprise gigabytes of spatio-temporal and temporal social network data, are made available to the research community.