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The distance between homes and childcare providers serves as a crucial factor in evaluating accessibility and equity in early childhood education. Spatial mismatch between childcare demand and supply is suggested when families opt for facilities further than the nearest available options, a situation scarcely scrutinized in existing literature, especially among under-six children from economically disadvantaged backgrounds. To fill this research gap, this study leverages the excess commuting analysis to delve into the extent of extended travel undertaken by subsidized families to access childcare services. Utilizing real enrollment data from the Florida’s School Readiness program, it quantifies the disparity between actual and shortest possible commuting distances, investigating the tendencies of low-income families to forgo nearby providers for their young children. Furthermore, the research probes into age-related disparities in excess commuting, examining to what degree childcare facilities are more conveniently located for certain age groups compared to others. The analysis unveils substantial spatial mismatch in subsidized childcare, with a significant portion of low-income families choosing more distant providers, resulting in a 51.3% surplus in commuting distance. It also highlights a noticeable age- dependent trend in this mismatch: parents of infants face a dual disadvantage with longer commutes, compared to families with five-year-olds who have closer access to providers. The findings advocate for policy reforms that address these disparities, enhancing the efficiency and equity of childcare resource allocation. 

Azaserine is a bacterial metabolite containing a biologically unusual and synthetically enabling α‐diazoester functional group. Herein, we report the discovery of the azaserine (aza) biosynthetic gene cluster fromGlycomyces harbinensis. Discovery of related gene clusters reveals previously unappreciated azaserine producers, and heterologous expression of theazagene cluster confirms its role in azaserine assembly. Notably, this gene cluster encodes homologues of hydrazonoacetic acid (HYAA)‐producing enzymes, implicating HYAA in α‐diazoester biosynthesis. Isotope feeding and biochemical experiments support this hypothesis. These discoveries indicate that a 2‐electron oxidation of a hydrazonoacetyl intermediate is required for α‐diazoester formation, constituting a distinct logic for diazo biosynthesis. Uncovering this biological route for α‐diazoester synthesis now enables the production of a highly versatile carbene precursor in cells, facilitating approaches for engineering complete carbene‐mediated biosynthetic transformations in vivo.