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NA (Ed.)Pacinian corpuscles detect transient touch and vibration in vertebrates. Corpuscles are composed of a mechanoreceptor afferent surrounded by lamellar Schwann cells (LSCs), enclosed by a multilayered outer core. The spatial arrangement of these components and their contribution to sensory tuning are unclear. We report the three-dimensional architecture of the Pacinian corpuscle and reveal the role of its cellular components in touch detection. In the prevailing model, the outer core acts as a mechanical filter that limits static and low-frequency stimuli from reaching the afferent terminal—the presumed sole site of touch detection. We show that the outer core is dispensable for the sensory tuning to transient touch and vibration; instead, these properties arise from the inner core. By acting as additional touch sensors, LSCs potentiate mechanosensitivity of the terminal, which detects touch via fast inactivating ion channels. Thus, functional tuning of the Pacinian corpuscle is enabled by an interplay between mechanosensitive LSCs and the afferent terminal in the inner core.more » « less
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Abstract The Hawaiian Ridge, a classic intraplate volcanic chain in the Central Pacific Ocean, has long attracted researchers due to its origin, eruption patterns, and impact on lithospheric deformation. Thought to arise from pressure‐release melting within a mantle plume, its mass‐induced deformation of Earth's surface depends on load distribution and lithospheric properties, including elastic thickness (Te). To investigate these features, a marine geophysical campaign was carried out across the Hawaiian Ridge in 2018. Westward of the island of O'ahu, a seismic tomographic image, validated by gravity data, reveals a large mass of volcanic material emplaced on the oceanic crust, flanked by an apron of volcaniclastic material filling the moat created by plate flexure. The ridge adds ∼7 km of material to pre‐existing ∼6‐km‐thick oceanic crust. A high‐velocity and high‐density core resides within the volcanic edifice, draped by alternating lava flows and mass wasting material. Beneath the edifice, upper mantle velocities are slightly higher than that of the surrounding mantle, and there is no evidence of extensive magmatic underplating of the crust. There is ∼3.5 km of downward deflection of the sediment‐crust and crust‐mantle boundaries due to flexure in response to the volcanic load. At Ka'ena Ridge, the volcanic edifice's height and cross‐sectional area are no more than half as large as those determined at Hawai'i Island. Together, these studies confirm that volcanic loads to the west of Hawai'i are largely compensated by flexure. Comparisons to the Emperor Seamount Chain confirm the Hawaiian Ridge's relatively stronger lithospheric rigidity.more » « less
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Graph neural networks (GNNs) have emerged as a powerful tool for tasks such as node classification and graph classification. However, much less work has been done on signal classification, where the data consists of many functions (referred to as signals) defined on the vertices of a single graph. These tasks require networks designed differently from those designed for traditional GNN tasks. Indeed, traditional GNNs rely on localized low-pass filters, and signals of interest may have intricate multi-frequency behavior and exhibit long range interactions. This motivates us to introduce the BLIS-Net (Bi-Lipschitz Scattering Net), a novel GNN that builds on the previously introduced geometric scattering transform. Our network is able to capture both local and global signal structure and is able to capture both low-frequency and high-frequency information. We make several crucial changes to the original geometric scattering architecture which we prove increase the ability of our network to capture information about the input signal and show that BLIS-Net achieves superior performance on both synthetic and real-world data sets based on traffic flow and fMRI data.more » « less
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Abstract The Hawaiian Ridge has long been a focus site for studying lithospheric flexure due to intraplate volcano loading, but crucial load and flexure details remain unclear. We address this problem using wide‐angle seismic refraction and reflection data acquired along a ∼535‐km‐long profile that intersects the ridge between the islands of Maui and Hawai'i and crosses 80–95 Myr‐old lithosphere. A tomographic image constructed using travel time data of several seismic phases reveals broad flexure of Pacific oceanic crust extending up to ∼200–250 km either side of the Hawaiian Ridge, and vertically up to ∼6–7 km. TheP‐wave velocity structure, verified by gravity modeling, reveals that the west flank of Hawaii is comprised of extrusive lavas overlain by volcanoclastic sediments and a carbonate platform. In contrast, the Hāna Ridge, southeast of Maui, contains a high‐velocity core consistent with mafic or ultramafic intrusive rocks. Magmatic underplating along the seismic line is not evident. Reflectors at the top and bottom of the pre‐existing oceanic crust suggest a ∼4.5–6 km crustal thickness. Simple three‐dimensional flexure modeling with an elastic plate thickness,Te, of 26.7 km shows that the depths to the reflectors beneath the western flank of Hawai'i can be explained by volcano loading in which Maui and the older islands in the ridge contribute ∼43% to the flexure and the island of Hawai'i ∼51%. Previous studies, however, revealed a higherTebeneath the eastern flank of Hawai'i suggesting that isostatic compensation may not yet be complete at the youngest end of the ridge.more » « less
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