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Japanese adults typically have healthier lipid profiles than American and European adults and a lower prevalence and later onset of atherosclerotic cardiovascular disease (ASCVD). Many Japanese also have uniquely elevated levels of high-density lipoprotein cholesterol (HDL-C). The following analysis examined the relationship between HDL-C level and HDL-C peroxide content, a bioindicator of unhealthy lipid metabolism in Japanese adults. Blood samples were collected from 463 participants, 31–84 years of age, who lived in Tokyo. A second blood sample was collected 5 years later from 241 of the participants, allowing us to evaluate the temporal stability of the inverse correlation between HDL-C level and HDL-C peroxide content. Glucoregulation and inflammatory activity were assessed because both can be associated with dyslipidemia and HDL-C dysfunction. Obesity and central adiposity were also considered. Overall, women had healthier HDL-C profiles than men. Elevated HDL-C (>90 mg/dL) was common (16.6%) and found more often in women. Higher HDL-C peroxide content was associated with older age and central adiposity and incremented further when HA1c and CRP were higher. When assessed 5 years later, lower HDL-C peroxide content continued to be evident in adults with higher HDL-C. While similar associations have been described for other populations, most Japanese adults typically had healthier levels of HDL-C with lower HDL-C peroxide content than previously reported for American adults.more » « lessFree, publicly-accessible full text available December 1, 2025
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Research in cultural psychology over the last three decades has revealed the profound influence of culture on cognitive, emotional, and motivational processes shaping individuals into active agents. This article first appeared in the Annual Review of Psychology (2024). It first reviews four notable cultural dimensions believed to underlie cultural variations: independent versus interdependent self, individualism versus collectivism, tightness versus looseness of social norms, and relational mobility. Then it examines how ecology and geography shape human activities and give rise to organised systems of cultural practices and meanings, called eco-cultural complexes. In turn, the eco-cultural complex of each zone is instrumental in shaping a wide range of psychological processes, revealing a psychological diversity that extends beyond the scope of the current East–West literature. Finally, it explores how some of the non-Western cultural zones of today, namely Arab, East Asian, Latin American, and South Asian zones, and discusses how they may have contributed, to varying degrees, to the formation of the contemporary Western cultural zone.more » « less
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Research in cultural psychology over the last three decades has revealed the profound influence of culture on cognitive, emotional, and motivational processes shaping individuals into active agents. This article aims to show cultural psychology's promise in three key steps. First, we review four notable cultural dimensions believed to underlie cultural variations: independent versus interdependent self, individualism versus collectivism, tightness versus looseness of social norms, and relational mobility. Second, we examine how ecology and geography shape human activities and give rise to organized systems of cultural practices and meanings, called eco-cultural complexes. In turn, the eco-cultural complex of each zone is instrumental in shaping a wide range of psychological processes, revealing a psychological diversity that extends beyond the scope of the current East–West literature. Finally, we examine some of the non-Western cultural zones present today, including Arab, East Asian, Latin American, and South Asian zones, and discuss how they may have contributed, to varying degrees, to the formation of the contemporary Western cultural zone.more » « less
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Abstract Objective The present study examined whether the effect of neuroticism on brain structure is moderated by behavioral adjustment. Background Neuroticism is widely thought to be harmful to health. However, recent work using proinflammatory biomarkers showed that this effect depends on behavioral adjustment, the willingness and ability to adjust and cope with environmental contingencies, such as different opinions of others or unpredictable life situations. Here, we sought to extend this observation to “brain health” by testing total brain volume (TBV). Method Using a community sample of 125 Americans, we examined structural magnetic resonance imaging of the brain and quantified TBV. We tested whether the effect of neuroticism on TBV was moderated by behavioral adjustment, net of intracranial volume, age, sex, educational achievement, and race. Results Behavioral adjustment significantly moderated the effect of neuroticism on TBV, such that neuroticism was associated with lower TBV only when behavioral adjustment was low. There was no such effect when behavioral adjustment was high. Conclusion The present findings suggest that neuroticism is not debilitating to those who constructively cope with stress. Implications are further discussed.more » « less
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Abstract The coronavirus disease 2019 (COVID‐19) pandemic has taken a massive toll on human life worldwide. The case of the United States—the world's largest economy—is particularly noteworthy, since the country suffered a disproportionately larger number of deaths than all other countries during the first year of the pandemic. A careful analysis may shed new light on the multifaceted processes contributing to this failure and help us prepare ourselves not to repeat the same mistakes in the future. Cultural psychology offers unique insights by highlighting mutually reinforcing interactions across collective, cultural, and psychological factors. Here, we review extant evidence and argue that various factors at these disparate levels converged to foster an independent mode of action, which, in turn, undermined effective coping with the infectious disease. The lack of effective political leadership exacerbated the resulting dire state of the country. Drawing on this analysis, we discuss several policy recommendations at collective, cultural, and psychological levels.more » « less
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