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Abstract Recent progress in artificial nanomachines offers promising solutions to grand challenges in biochemical delivery and diagnostics. In this work, advances of micro/nanomachines made of synthesized micro/nanostructures for applications in delivery and detection of biomolecules are reviewed, along with a discussion of pros and cons of each type of machine. The review of micro/nanomachines is categorized according to their working mechanisms, including motion actuation realized by magnetic, electric, and acoustic fields and chemical reactions. The developments of micro/nanomachines are discussed in depth in the fabrication, propulsion, and motion control, loading and releasing of micro/nanosubstances, and biochemical sensing. The rapid development of man‐made miniaturized machines paves the road toward future intelligent nanorobots and nanofactories that can revolutionize society.
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Nanonetworks in Biomedical Applications
By interconnecting nanomachines and forming nanonetworks, the capacities of singlenanomachines are expected to be enhanced, as the ensuing information exchange will allow themto cooperate towards a common goal. Nowadays, systems normally use electromagnetic signals toencode, send and receive information, however, in a novel communication paradigm, moleculartransceivers, channel models or protocols use molecules. This article presents the current developmentsin nanomachines along with their future architecture to better understand nanonetworkscenarios in biomedical applications. Furthermore, to highlight the communication needs betweennanomachines, two applications for nanonetworks are also presented: i) a new networking paradigm,called the Internet of NanoThings, that allows nanoscale devices to interconnect with existingcommunication networks, and ii) Molecular Communication, where the propagation of chemicalcompounds like drug particles, carry out the information exchange.
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- PAR ID:
- 10101417
- Date Published:
- Journal Name:
- Current Drug Targets
- Volume:
- 20
- Issue:
- 8
- ISSN:
- 1389-4501
- Page Range / eLocation ID:
- 800 to 807
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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- Free Publicly Accessible Full Text
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Accepted Manuscript1.0
- Journal Article:
- https://doi.org/10.2174/1389450120666190115152613
